Extracellular vesicles: a novel window into kidney function and disease
- Authors
- Sun, In O.; Kwon, Soon Hyo
- Issue Date
- Nov-2020
- Publisher
- Lippincott Williams & Wilkins Ltd.
- Keywords
- biomarker; disease; exosomes; kidney; physiology
- Citation
- Current Opinion in Nephrology and Hypertension, v.29, no.6, pp 613 - 619
- Pages
- 7
- Journal Title
- Current Opinion in Nephrology and Hypertension
- Volume
- 29
- Number
- 6
- Start Page
- 613
- End Page
- 619
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2365
- DOI
- 10.1097/MNH.0000000000000641
- ISSN
- 1062-4821
1473-6543
- Abstract
- Purpose of review There has been an increasing interest in extracellular vesicles as potential diagnostic, prognostic or therapeutic biomarkers for various kidney diseases, as extracellular vesicles mediate cell-cell or intercellular communication. This review explores the current state of knowledge regarding extracellular vesicles as a tool for examining kidney physiology and disease. Recent findings Urinary extracellular vesicles may be useful as biomarkers to detect abnormal function in renal endothelial and tubular cells as well as podocytes. Recent studies suggest that urinary extracellular vesicles may facilitate early diagnosis and/or monitoring in acute kidney injury, glomerular disease, autosomal dominanat polycyst kidney disease and urinary tract malignancies. Circulating extracellular vesicles may serve as biomarkers to assess cardiovascular disease. Urinary and circulating extracellular vesicles have gained significant interest as potential biomarkers of renal diseases. Analysis of extracellular vesicles may serve as a logical diagnostic approach for nephrologists as well as provide information about disease pathophysiology.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2365)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.