Interactive tissue reactions of 1064-nm focused picosecond-domain laser and dermal cohesive polydensified matrix hyaluronic acid treatment in in vivo rat skin
DC Field | Value | Language |
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dc.contributor.author | Kim, Hee Kyung | - |
dc.contributor.author | Kim, Hyun-Jo | - |
dc.contributor.author | Hong, Jeong Yeon | - |
dc.contributor.author | Park, Jinyoung | - |
dc.contributor.author | Lee, Hee Chul | - |
dc.contributor.author | Lyu, Herin | - |
dc.contributor.author | Cho, Sung Bin | - |
dc.date.accessioned | 2021-08-11T08:33:02Z | - |
dc.date.available | 2021-08-11T08:33:02Z | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 0909-752X | - |
dc.identifier.issn | 1600-0846 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2537 | - |
dc.description.abstract | Background Picosecond-domain laser treatment using a microlens array (MLA) or a diffractive optical element (DOE) generates micro-injury zones in the epidermis and upper dermis. Objective To investigate interactive tissue reactions between MLA-type picosecond laser pulses and cohesive polydensified matrix hyaluronic acid (CPMHA) filler in the dermis. Methods In vivo rats with or without CPMHA pretreatment were treated with a 1064-nm picosecond-domain neodymium:yttrium-aluminum-garnet (Nd:YAG) laser using an MLA or DOE. Skin samples were obtained at post-treatment days 1, 10, and 21 and histologically and immunohistochemically analyzed. Results Picosecond-domain Nd:YAG laser treatment with an MLA-type or a DOE-type handpiece generated fractionated zones of pseudo-cystic cavitation along the lower epidermis and/or upper papillary dermis at Day 1. At Day 21, epidermal thickness, dermal fibroblasts, and collagen fibers had increased. Compared to CPMHA-untreated rats, rats pretreated with CPMHA showed marked increases in fibroblasts and collagen fibers in the papillary dermis. Immunohistochemical staining for the hyaluronic acid receptor CD44 revealed that MLA-type picosecond laser treatment upregulated CD44 expression in the basilar epidermis and dermal fibroblasts. Conclusions We suggest that the hyaluronic acid-rich environment associated with CPMHA treatment may enhance MLA-type picosecond-domain laser-induced tissue reactions in the epidermis and upper dermis. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Interactive tissue reactions of 1064-nm focused picosecond-domain laser and dermal cohesive polydensified matrix hyaluronic acid treatment in in vivo rat skin | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/srt.12853 | - |
dc.identifier.scopusid | 2-s2.0-85081749422 | - |
dc.identifier.wosid | 000563533600001 | - |
dc.identifier.bibliographicCitation | Skin Research and Technology, v.26, no.5, pp 683 - 689 | - |
dc.citation.title | Skin Research and Technology | - |
dc.citation.volume | 26 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 683 | - |
dc.citation.endPage | 689 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | ALEXANDRITE LASER | - |
dc.subject.keywordPlus | CD44 | - |
dc.subject.keywordPlus | PROTEOGLYCAN | - |
dc.subject.keywordAuthor | CD44 | - |
dc.subject.keywordAuthor | cohesive polydensified matrix hyaluronic acid | - |
dc.subject.keywordAuthor | laser | - |
dc.subject.keywordAuthor | laser-induced tissue breakdown | - |
dc.subject.keywordAuthor | neodymium-doped yttrium aluminum garnet | - |
dc.subject.keywordAuthor | picosecond | - |
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