A Flexible and Transparent PtNP/SWCNT/PET Electrochemical Sensor for Nonenzymatic Detection of Hydrogen Peroxide Released from Living Cells with Real-Time Monitoring Capability
DC Field | Value | Language |
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dc.contributor.author | Oh, Da Eun | - |
dc.contributor.author | Lee, Chang-Seuk | - |
dc.contributor.author | Kim, Tae Wan | - |
dc.contributor.author | Jeon, Seob | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.date.accessioned | 2023-12-14T06:30:43Z | - |
dc.date.available | 2023-12-14T06:30:43Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 2079-6374 | - |
dc.identifier.issn | 2079-6374 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/25387 | - |
dc.description.abstract | We developed a transparent and flexible electrochemical sensor using a platform based on a network of single-walled carbon nanotubes (SWCNTs) for the non-enzymatic detection of hydrogen peroxide (H2O2) released from living cells. We decorated the SWCNT network on a poly(ethylene terephthalate) (PET) substrate with platinum nanoparticles (PtNPs) using a potentiodynamic method. The PtNP/SWCNT/PET sensor synergized the advantages of a flexible PET substrate, a conducting SWCNT network, and a catalytic PtNP and demonstrated good biocompatibility and flexibility, enabling cell adhesion. The PtNP/SWCNT/PET-based sensor demonstrated enhanced electrocatalytic activity towards H2O2, as well as excellent selectivity, stability, and reproducibility. The sensor exhibited a wide dynamic range of 500 nM to 1 M, with a low detection limit of 228 nM. Furthermore, the PtNP/SWCNT/PET sensor remained operationally stable, even after bending at various angles (15 & DEG;, 30 & DEG;, 60 & DEG;, and 90 & DEG;), with no noticeable loss of current signal. These outstanding characteristics enabled the PtNP/SWCNT/PET sensor to be practically applied for the direct culture of HeLa cells and the real-time monitoring of H2O2 release by the HeLa cells under drug stimulation. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | A Flexible and Transparent PtNP/SWCNT/PET Electrochemical Sensor for Nonenzymatic Detection of Hydrogen Peroxide Released from Living Cells with Real-Time Monitoring Capability | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/bios13070704 | - |
dc.identifier.scopusid | 2-s2.0-85165934236 | - |
dc.identifier.wosid | 001038045600001 | - |
dc.identifier.bibliographicCitation | BIOSENSORS-BASEL, v.13, no.7 | - |
dc.citation.title | BIOSENSORS-BASEL | - |
dc.citation.volume | 13 | - |
dc.citation.number | 7 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | H2O2 | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | ELECTRODE | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | NANOHYBRID | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordAuthor | electrochemical sensing | - |
dc.subject.keywordAuthor | flexible sensor | - |
dc.subject.keywordAuthor | hydrogen peroxide (H2O2) | - |
dc.subject.keywordAuthor | platinum nanoparticles | - |
dc.subject.keywordAuthor | single-walled carbon nanotube (SWCNT) network | - |
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