만성 폐쇄성 폐질환으로 저용량 스테로이드 유지 중인 환자에게 발생한 Nocardia abscessus에 의한 다발성 근육 농양 1예open accessMultiple Intramuscular Abscesses Caused by Nocardia abscessus in a Patient with Chronic Obstructive Lung Disease: Clinical Microbiology Considerations
- Other Titles
- Multiple Intramuscular Abscesses Caused by Nocardia abscessus in a Patient with Chronic Obstructive Lung Disease: Clinical Microbiology Considerations
- Authors
- 김정아; 동현주; 이은정; 정종탁; 백예지; 김태형; 최태윤
- Issue Date
- Feb-2024
- Publisher
- 대한내과학회
- Keywords
- Nocardia abscessus; 근육 내 농양; 면역저하자; MALDI-MS; Nocardia abscessus; Intramuscular abscess; Immunocompromised host; MALDI-MS
- Citation
- 대한내과학회지, v.99, no.1, pp 50 - 56
- Pages
- 7
- Journal Title
- 대한내과학회지
- Volume
- 99
- Number
- 1
- Start Page
- 50
- End Page
- 56
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/25982
- DOI
- 10.3904/kjm.2024.99.1.50
- ISSN
- 1738-9364
2289-0769
- Abstract
- Nocardiosis is uncommon. Immunocompromising conditions predispose individuals to pulmonary and disseminated nocardiosis of the brain, skin, and subcutaneous tissues. The most common pathogens are Nocardia cyriacigeorgica, Nocardia nova, and Nocardia farcinica. The speciation of Nocardia to determine antimicrobial susceptibility is difficult using traditional biochemical methods. Here, we report the case of a 73-year-old man with chronic obstructive lung disease who developed a rapidly progressing intramuscular abscess around the left hip and thigh. Within 3 days, the lesions progressed to an epidural abscess at the L4 to S1 level. Although he was treated with broad-spectrum antibiotics and extensive incision and drainage, he died of rapidly progressive respiratory failure. Nocardia abscessus (N. abscessus) was identified in pus samples using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). This case shows that the diagnosis of an intramuscular abscess caused by N. abscessus is challenging and that using MALDI-TOF MS may facilitate the diagnosis and ensure appropriate treatment.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Clinical Pathology > 1. Journal Articles
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