의사에게 요구되는 인간이해를 통합한 질병발생모델의 제안open accessHuman Understanding is Expected of the Physician: Proposing a Model of Disease Development
- Other Titles
- Human Understanding is Expected of the Physician: Proposing a Model of Disease Development
- Authors
- 박상흠; 박삼엘; 김진영; 이현아; 이상미; 이태훈; 배상병; 장성혜; 장시형; 전성완; 문종호
- Issue Date
- Apr-2024
- Publisher
- 대한내과학회
- Keywords
- 인간이해; 질병발생; 염증; 4단계 습관고리; 적응반응; Human understanding; Disease development; Inflammation; Four-step habit loop; Adaptive response
- Citation
- 대한내과학회지, v.99, no.2, pp 84 - 95
- Pages
- 12
- Journal Title
- 대한내과학회지
- Volume
- 99
- Number
- 2
- Start Page
- 84
- End Page
- 95
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26148
- DOI
- 10.3904/kjm.2024.99.2.84
- ISSN
- 1738-9364
2289-0769
- Abstract
- In Harrison’s Principles of Internal Medicine, human understanding is emphasized as one of three necessary characteristics that a physician must have. Inflammation, which is caused by inflammatory inducers (inf-ids), is a fundamental feature of disease at the cellular and molecular levels. Inflammation protects the body, but excessive or prolonged inflammation can be damaging and can cause disease. Humans are repeatedly exposed to external and internal environmental factors that generate inf-ids throughout their lives. External environmental factors include microbial and non-microbial inf-ids, as well as stressors that inevitably arise during social interactions. Internal environmental factors include the adaptive physiological response that is present from birth. Inf-ids may also be produced by the four-step habit loop, which consists of a cue (e.g., stressor), emotions, routine act (adaptive response), and a reward. Immune cells in the circulatory system and in tissues may have positive and negative effects in inflammatory responses. However, low-grade inflammation may be difficult to detect. We propose a model of disease development that integrates external and internal environmental factors from the perspective of human understanding.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Psychiatry > 1. Journal Articles
- College of Medicine > Department of Pathology > 1. Journal Articles
- College of Medicine > Department of Internal Medicine > 1. Journal Articles
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