Effects of Treating Subclinical Rejection 2 Weeks After Kidney Transplantation, as Determined by Analyzing 1-Year Histologic Outcomes
DC Field | Value | Language |
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dc.contributor.author | Lee, Okjo | - |
dc.contributor.author | Kim, Min Jung | - |
dc.contributor.author | Lee, Jung Eun | - |
dc.contributor.author | Kwon, Ghee Young | - |
dc.contributor.author | Hwang, Na Young | - |
dc.contributor.author | Kim, Kyunga | - |
dc.contributor.author | Park, Jae Berm | - |
dc.contributor.author | Lee, Kyo Won | - |
dc.date.accessioned | 2024-08-14T05:02:00Z | - |
dc.date.available | 2024-08-14T05:02:00Z | - |
dc.date.issued | 2023-05 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.issn | 1873-2623 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/26545 | - |
dc.description.abstract | Subclinical rejection (SCR) is associated with chronic allograft nephropathy. Therefore, early detection and treatment of SCR through a protocol biopsy (PB) can reduce the incidence of pathologic changes. This study evaluates the impact of early detection and treatment of SCR using a routine PB 2 weeks after kidney transplantation (KT) by examining histologic outcomes 1 year later. We reviewed 624 KT recipients at the Samsung Medical Center between August 2012 and December 2018. Protocol biopsy was planned 2 weeks and 1 year after transplantation. We compared the histologic changes between the 2 biopsies. After a propensity score matching analysis, we divided the patients into 2 groups: the proven normal group (n = 256) and the rejection group (n = 96) at the PB taken 2 weeks post-transplant. The rejection group showed no significant difference from the normal group in the flow of graft function or the Kaplan-Meier curve for graft survival. In the histologic outcomes, the pathologic differences between the groups significantly improved between the 2 time points. Treating SCR through a PB 2 weeks after KT can contribute to the maintenance of graft function and improve histologic changes 1 year after KT. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Effects of Treating Subclinical Rejection 2 Weeks After Kidney Transplantation, as Determined by Analyzing 1-Year Histologic Outcomes | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1016/j.transproceed.2023.03.005 | - |
dc.identifier.scopusid | 2-s2.0-85152524275 | - |
dc.identifier.wosid | 001018023700001 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, v.55, no.4, pp 769 - 776 | - |
dc.citation.title | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.volume | 55 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 769 | - |
dc.citation.endPage | 776 | - |
dc.type.docType | Article; Early Access | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | PROTOCOL BIOPSY | - |
dc.subject.keywordPlus | RENAL-TRANSPLANTATION | - |
dc.subject.keywordPlus | IMPACT | - |
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