Age-Related Changes in Auditory Nogo-N200 Latency in Medication-Naive Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
- Authors
- Lee, Yeon Jung; Jeong, Mi Young; Park, Seoyoung; Kim, Jung Ho; Kim, Ji-Sun; Woo, Sung-Il
- Issue Date
- Jul-2020
- Publisher
- 대한신경정신의학회
- Keywords
- Attention-deficit/hyperactivity disorder; Evoked potentials; Electroencephalography; Child; Adolescent
- Citation
- PSYCHIATRY INVESTIGATION, v.17, no.7, pp 702 - 709
- Pages
- 8
- Journal Title
- PSYCHIATRY INVESTIGATION
- Volume
- 17
- Number
- 7
- Start Page
- 702
- End Page
- 709
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2671
- DOI
- 10.30773/pi.2020.0083
- ISSN
- 1738-3684
1976-3026
- Abstract
- Objective Event-related potential (ERP) changes with brain development in healthy children and adolescents. However, few studies have focused on age-related changes in the N200 and P300 components among individuals with attention-deficit/hyperactivity disorder (ADHD). Therefore, this study aimed to assess age-related differences in the auditory nogo-N200 components in individuals with ADHD. Methods We enrolled 46 participants with auditory nogo-N200 and nogo-P300 components. We assessed ADHD symptoms using the Advanced Test of Attention (ATA) and Korean ADHD Rating Scale-IV (K-ARS-IV). Moreover, we assessed emotional and behavioral problems using the Korean Child Behavior Checklist (K-CBCL). Further, we measured auditory ERPs. Results There were no differences with respect to sex or ATA, K-ARS-IV, and K-CBCL scores between the groups. With a 1-year increase in age, the nogo-N200 latency at Fz and Cz decreased by 6.08 ms and 4.88 ms, respectively; this result was statistically significant in multivariable linear regression adjusted by sex and dominant hand. Conclusion Our findings revealed age-related changes in nogo-N200 latency at the Fz and Cz electrodes in individuals with ADHD. Future studies should perform comparisons with healthy controls to determine whether auditory nogo-N200 can be used to evaluate the developmental level in individuals with ADHD.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Psychiatry > 1. Journal Articles
- College of Medicine > Department of Psychiatry > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/2671)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.