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Electrochemical oxidative iodination of imidazo[1,2-a]pyridines using NaI as iodine source

Authors
Park, Jin WhaKim, Yong HwanKim, Dae Young
Issue Date
3-Mar-2020
Publisher
Marcel Dekker Inc.
Keywords
Electrochemical oxidation; imidazo[12-a]pyridines; iodination; 3-iodoimidazo[1; 2-a]pyridines
Citation
Synthetic Communications, v.50, no.5, pp 710 - 718
Pages
9
Journal Title
Synthetic Communications
Volume
50
Number
5
Start Page
710
End Page
718
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/3002
DOI
10.1080/00397911.2020.1717539
ISSN
0039-7911
1532-2432
Abstract
An electrochemical oxidative iodination of imidazo[1,2-a]pyridines is achieved in this study. This reaction utilizes NaI as an iodine source and a supporting electrolyte under metal-free and exogenous chemical oxidant-free reaction conditions. The present protocol provides an efficient route to prepare 3-iodoimidazo[1,2-a]pyridines derivatives.
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