Treatment Satisfaction with Flexible-dose Fesoterodine in Patients with Overactive Bladder who were Dissatisfied with Previous Anticholinergic Therapy: A Multicenter Single-Arm Clinical Study
DC Field | Value | Language |
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dc.contributor.author | Choi, Jin Bong | - |
dc.contributor.author | Cho, Kang Jun | - |
dc.contributor.author | Park, Won Hee | - |
dc.contributor.author | Lee, Dong Hwan | - |
dc.contributor.author | Kim, Young-Ho | - |
dc.contributor.author | Cho, In Rae | - |
dc.contributor.author | Yoon, Hana | - |
dc.contributor.author | Kim, Young Sik | - |
dc.contributor.author | Kim, Joon Chul | - |
dc.date.accessioned | 2021-08-11T08:38:57Z | - |
dc.date.available | 2021-08-11T08:38:57Z | - |
dc.date.issued | 2020-01 | - |
dc.identifier.issn | 1735-1308 | - |
dc.identifier.issn | 1735-546X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/3220 | - |
dc.description.abstract | Purpose: We investigated treatment satisfaction with flexible-dose fesoterodine in patients with overactive bladder (OAB) who were dissatisfied with previous anticholinergic therapy. Materials and Methods: The subjects were prescribed fesoterodine 4 mg for 4 weeks and fesoterodine 4 mg or 8 mg for another 8 weeks. The primary end point of this study was patients' satisfaction after 12 weeks of fesoterodine treatment on a five-point Likert scale. Secondary end points included a change in the number of daytime micturition, urgency incontinence episodes, urgency episodes, and nocturnal micturition in a -24hour period from baseline to final assessment. Results: Overall, 84 patients were assigned to the treatment group in this study and 63 patients completed the -12week treatment course. A final fesoterodine dose of 4 mg and 8 mg was used by %71.4) 45) and %28.6) 18) patients, respectively. The satisfaction and dissatisfaction rates at 12 weeks were %69.9 and %14.2, respectively. Mean changes in the daytime micturitions (4.72 +/- 9.73 vs. 2.86 +/- 7.76), urgency episodes (5.68 +/- 7.73 vs. +/- 3.71 4.09), and nocturnal micturitions (1.36 +/- 2.13 vs. 1.12 +/- 1.68) in 24 hours improved significantly with flexible-dose fesoterodine treatment (P < .05). Most adverse events were mild and none were severe. Conclusion: The flexible dose fesoterodine represents an alternative treatment modality in patients with OAB who are dissatisfied with previous anticholinergic therapy in Korea. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Urology and Nephrology Research Center | - |
dc.title | Treatment Satisfaction with Flexible-dose Fesoterodine in Patients with Overactive Bladder who were Dissatisfied with Previous Anticholinergic Therapy: A Multicenter Single-Arm Clinical Study | - |
dc.type | Article | - |
dc.publisher.location | 이란 | - |
dc.identifier.doi | 10.22037/uj.v0i0.4650 | - |
dc.identifier.scopusid | 2-s2.0-85071902619 | - |
dc.identifier.wosid | 000535754800017 | - |
dc.identifier.bibliographicCitation | Urology journal, v.17, no.1, pp 97 - 101 | - |
dc.citation.title | Urology journal | - |
dc.citation.volume | 17 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 97 | - |
dc.citation.endPage | 101 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | DOUBLE-BLIND | - |
dc.subject.keywordPlus | OPEN-LABEL | - |
dc.subject.keywordPlus | 8 MG | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | PLACEBO | - |
dc.subject.keywordPlus | URGENCY | - |
dc.subject.keywordPlus | INCONTINENCE | - |
dc.subject.keywordAuthor | fesoterodine | - |
dc.subject.keywordAuthor | overactive bladder | - |
dc.subject.keywordAuthor | patient satisfaction | - |
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