부비동 내시경 수술 후 발생한 점막의 폴립양 변화에 대해 트리암시놀론을 함유한 젤폼의 효과open accessThe Effect of Triamcinolone-Soaked Gelfoam in Patients with Polypoid Mucosal Change after Endoscopic Sinus Surgery
- Other Titles
- The Effect of Triamcinolone-Soaked Gelfoam in Patients with Polypoid Mucosal Change after Endoscopic Sinus Surgery
- Authors
- 류광희; 조영상; 홍상덕; 김효열; 정승규; 동헌종
- Issue Date
- 2020
- Publisher
- 대한비과학회
- Keywords
- Nasal polyp; Polypoid change; Triamcinolone; Gelfoam.
- Citation
- Journal of Rhinology, v.27, no.1, pp 16 - 20
- Pages
- 5
- Journal Title
- Journal of Rhinology
- Volume
- 27
- Number
- 1
- Start Page
- 16
- End Page
- 20
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/3553
- DOI
- 10.18787/jr.2019.00288
- ISSN
- 1229-1498
2384-4361
- Abstract
- Background and Objectives: Chronic rhinosinusitis with nasal polyps (CRSwNP) recurs frequently after endoscopic sinus surgery (ESS). The aim of study was to evaluate the efficacy of triamcinolone-soaked absorbable gelatin foam (gelfoam) as a treatment for recurred polypoid changes after ESS.Subjects and Method: A total of 35 patients and 57 nasal cavities was retrospectively reviewed. All patients underwent triamcinolone- infused gelfoam packing for 1 week under nasal endoscopic guidance. Endoscopic scores were evaluated at 1 week, 1 month, and 3 months. We analyzed clinical characteristics between success and failure groups.Results: Endoscopic scores were significantly improved after triamcinolone-soaked gelfoam packing, and the effects were maintained at 3-month follow-up (1.85±0.61 vs. 0.82±0.77, p<0.001). Duration between surgery and gelfoam packing was shorter in the success group compared to the failure group (8.2±6.9 vs. 13.7±8.4 weeks, p=0.033). Serum eosinophil cationic protein and tissue eosinophil counts were significantly higher in the failure group (p=0.025 and p=0.010, respectively).Conclusion: Triamcinolone-soaked gelfoam packing is an effective and safe method for managing recurrent polypoid change in patients with CRSwNP after ESS. Early intervention contributed to a successful result, and eosinophilic inflammation was associated with poor outcomes.
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Collections - College of Medicine > Department of Otorhinolaryngology > 1. Journal Articles
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