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Treatment of Hidradenitis Suppurativa Patient with Klinefelter Syndrome by Adalimumab

Authors
Shin, Ji YeounHong, Jung YeonLee, Ho JungSim, Chang YoonPark, Young LipLee, Jong SukLee, Sung YulKim, Jung Eun
Issue Date
Aug-2019
Publisher
대한피부과학회
Keywords
Hidradenitis suppurativa; Klinefelter syndrome
Citation
Annals of Dermatology, v.31, no.4, pp 446 - 449
Pages
4
Journal Title
Annals of Dermatology
Volume
31
Number
4
Start Page
446
End Page
449
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4358
DOI
10.5021/ad.2019.31.4.446
ISSN
1013-9087
2005-3894
Abstract
Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an increased risk of metabolic disorders such as diabetes, metabolic syndrome and autoimmune diseases. Klinefelter syndrome (KS) is a sex chromosomal disorder occurring in males due to an abnormality of sexual differentiation, characterized by 47, XXY karyotype. Also, KS is related with somatic comorbidities such as metabolic syndrome, autoimmune and rheumatologic disorders as HS is. We report a HS patient with KS who shows a big improvement while on tumor necrosis factor-alpha inhibitor treatment.
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