Clinical usefulness of two-phase F-18-sodium-fluoride (F-18-NaF) bone PET/CT for evaluating treatment response of bone metastases from breast cancer: Case report
- Authors
- Seo, J. H.; Lee, S. M.; Yu, S. N.; Lee, J. W.; Lee, J. E.
- Issue Date
- Jul-2019
- Publisher
- Elsevier Espana
- Keywords
- Positron emission tomography; F-18-sodium fluoride; Breast cancer
- Citation
- Revista Espanola de Medicina Nuclear e Imagen Molecular, v.38, no.4, pp 238 - 242
- Pages
- 5
- Journal Title
- Revista Espanola de Medicina Nuclear e Imagen Molecular
- Volume
- 38
- Number
- 4
- Start Page
- 238
- End Page
- 242
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4415
- DOI
- 10.1016/j.remn.2018.09.009
- ISSN
- 2253-654X
- Abstract
- We report the case of a breast cancer patient in whom a two-phase F-18-sodium-fluoride (F-18-NaF) bone PET/CT was useful for detecting hidden bone metastases and assessing treatment response. The patient underwent a two-phase bone PET/CT to evaluate a newly developed lesion found on bone scintigraphy following surgery. In the perfusion and bone phase PET/CT images, focally increased perfusion and bony uptake were found in the sacrum and L5 vertebra, suggesting bone metastases of breast cancer. Therefore, the patient subsequently underwent palliative treatment. In another two PET/CT studies (each including two-phase bone images) performed after 3 and 6 months of follow-up, the perfusion phase images showed an improvement of the lesion uptake more clearly than in the bone phase images in the visual and semi-quantitative analyses, and thus the perfusion phase images were more useful for clarifying the treatment response earlier than the bone phase images. This is the first case showing the clinical usefulness of F-18-NaF bone PET/CT with the perfusion imaging technique for evaluating bone metastases and the therapeutic response of metastatic bone lesions. (C) 2019 Sociedad Espanola de Medicina Nuclear e Imagen Molecular. Published by Elsevier Espana, S.L.U. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
- College of Medicine > Department of Radiology > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4415)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.