Electrochemical Detection of Ultratrace Lead Ion through Attaching and Detaching DNA Aptamer from Electrochemically Reduced Graphene Oxide Electrode
DC Field | Value | Language |
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dc.contributor.author | Yu, Su Hwan | - |
dc.contributor.author | Lee, Chang-Seuk | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.date.accessioned | 2021-08-11T09:43:51Z | - |
dc.date.available | 2021-08-11T09:43:51Z | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 2079-4991 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4479 | - |
dc.description.abstract | This paper describes a simple strategy for the ultratrace level detection of Pb2+ ion based on G-quadruplex DNA and an electrochemically reduced graphene oxide (ERGO) electrode. First, ERGO was formed on a glassy carbon electrode (GCE) by the reduction of graphene oxide (GO) using cyclic voltammetry. Subsequently, a methylene blue (MB)-tagged, guanine-rich DNA aptamer (Apt) was attached to the surface of ERGO via pi-pi interaction, leading to the Apt-modified ERGO electrode. The presence of Pb2+ could generate the folding of Apt to a G-quadruplex structure. The formation of G-quadruplex resulted in detaching the Apt from the ERGO/GCE, leading to a change in redox current of the MB tag. Electrochemical measurements showed the proposed sensor had an exceptional sensitivity for Pb2+ with a linear range from 10(-15) to 10(-9) M and a detection limit of 0.51 fM. The sensor also exhibited high selectivity for Pb2+, as well as many other advantages, such as stability, reproducibility, regeneration, as well as simple fabrication and operation processes. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Electrochemical Detection of Ultratrace Lead Ion through Attaching and Detaching DNA Aptamer from Electrochemically Reduced Graphene Oxide Electrode | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/nano9060817 | - |
dc.identifier.scopusid | 2-s2.0-85068452567 | - |
dc.identifier.wosid | 000475352900011 | - |
dc.identifier.bibliographicCitation | Nanomaterials, v.9, no.6 | - |
dc.citation.title | Nanomaterials | - |
dc.citation.volume | 9 | - |
dc.citation.number | 6 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | GLASSY-CARBON ELECTRODE | - |
dc.subject.keywordPlus | HEAVY-METAL IONS | - |
dc.subject.keywordPlus | COORDINATION CHEMISTRY | - |
dc.subject.keywordPlus | HEMIN/G-QUADRUPLEX | - |
dc.subject.keywordPlus | DNAZYME | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordAuthor | reduced graphene oxide | - |
dc.subject.keywordAuthor | G-quadruplex | - |
dc.subject.keywordAuthor | lead ion | - |
dc.subject.keywordAuthor | electrochemical aptasensor | - |
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