Visceral adipose tissue volume and CT-attenuation as prognostic factors in patients with head and neck cancer
DC Field | Value | Language |
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dc.contributor.author | Lee, Jeong Won | - |
dc.contributor.author | Ban, Myung Jin | - |
dc.contributor.author | Park, Jae Hong | - |
dc.contributor.author | Lee, Sang Mi | - |
dc.date.accessioned | 2021-08-11T09:43:56Z | - |
dc.date.available | 2021-08-11T09:43:56Z | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 1043-3074 | - |
dc.identifier.issn | 1097-0347 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4506 | - |
dc.description.abstract | Background The aim of this study was to evaluate the relationship of the characteristics of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) to the disease progression-free survival and distant failure-free survival of head and neck squamous cell carcinoma (HNSCC). Methods We enrolled 152 HNSCC patients who underwent staging F-18-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT). Maximum FDG uptake (standardized uptake value [SUV]) and total lesion glycolysis (TLG) of the primary tumor and volume, CT-attenuation (Hounsfield units [HU]), and FDG uptake of SAT and VAT were measured. Survival analysis using Cox proportional hazard modeling was performed to assess the relationship between the adipose tissue parameters of PET/CT and survival. Results Patients with low VAT volume and high VAT HU had significantly worse progression-free survival and distant failure-free survival than those with high VAT volume and low VAT HU. On multivariate analysis, the volume and HU of VAT were significantly correlated with disease progression-free survival and distant failure-free survival after adjusting for age, sex, body mass index, TNM stage, serum C-reactive protein, maximum SUV, and TLG. Conclusion The volume and CT-attenuation of VAT were significantly correlated with disease progression-free survival and distant failure-free survival in patients with HNSCC. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley & Sons Inc. | - |
dc.title | Visceral adipose tissue volume and CT-attenuation as prognostic factors in patients with head and neck cancer | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1002/hed.25605 | - |
dc.identifier.scopusid | 2-s2.0-85059894367 | - |
dc.identifier.wosid | 000468629500011 | - |
dc.identifier.bibliographicCitation | Head and Neck, v.41, no.6, pp 1605 - 1614 | - |
dc.citation.title | Head and Neck | - |
dc.citation.volume | 41 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1605 | - |
dc.citation.endPage | 1614 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | NASOPHARYNGEAL CARCINOMA | - |
dc.subject.keywordPlus | PREDICTING MORTALITY | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | FAT | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordAuthor | adipose tissue | - |
dc.subject.keywordAuthor | fluorodeoxyglucose F18 | - |
dc.subject.keywordAuthor | head and neck cancer | - |
dc.subject.keywordAuthor | positron emission tomography | - |
dc.subject.keywordAuthor | prognosis | - |
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