Detailed Information

Cited 0 time in webofscience Cited 22 time in scopus
Metadata Downloads

Visceral adipose tissue volume and CT-attenuation as prognostic factors in patients with head and neck cancer

Full metadata record
DC Field Value Language
dc.contributor.authorLee, Jeong Won-
dc.contributor.authorBan, Myung Jin-
dc.contributor.authorPark, Jae Hong-
dc.contributor.authorLee, Sang Mi-
dc.date.accessioned2021-08-11T09:43:56Z-
dc.date.available2021-08-11T09:43:56Z-
dc.date.issued2019-06-
dc.identifier.issn1043-3074-
dc.identifier.issn1097-0347-
dc.identifier.urihttps://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4506-
dc.description.abstractBackground The aim of this study was to evaluate the relationship of the characteristics of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) to the disease progression-free survival and distant failure-free survival of head and neck squamous cell carcinoma (HNSCC). Methods We enrolled 152 HNSCC patients who underwent staging F-18-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT). Maximum FDG uptake (standardized uptake value [SUV]) and total lesion glycolysis (TLG) of the primary tumor and volume, CT-attenuation (Hounsfield units [HU]), and FDG uptake of SAT and VAT were measured. Survival analysis using Cox proportional hazard modeling was performed to assess the relationship between the adipose tissue parameters of PET/CT and survival. Results Patients with low VAT volume and high VAT HU had significantly worse progression-free survival and distant failure-free survival than those with high VAT volume and low VAT HU. On multivariate analysis, the volume and HU of VAT were significantly correlated with disease progression-free survival and distant failure-free survival after adjusting for age, sex, body mass index, TNM stage, serum C-reactive protein, maximum SUV, and TLG. Conclusion The volume and CT-attenuation of VAT were significantly correlated with disease progression-free survival and distant failure-free survival in patients with HNSCC.-
dc.format.extent10-
dc.language영어-
dc.language.isoENG-
dc.publisherJohn Wiley & Sons Inc.-
dc.titleVisceral adipose tissue volume and CT-attenuation as prognostic factors in patients with head and neck cancer-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1002/hed.25605-
dc.identifier.scopusid2-s2.0-85059894367-
dc.identifier.wosid000468629500011-
dc.identifier.bibliographicCitationHead and Neck, v.41, no.6, pp 1605 - 1614-
dc.citation.titleHead and Neck-
dc.citation.volume41-
dc.citation.number6-
dc.citation.startPage1605-
dc.citation.endPage1614-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaOtorhinolaryngology-
dc.relation.journalResearchAreaSurgery-
dc.relation.journalWebOfScienceCategoryOtorhinolaryngology-
dc.relation.journalWebOfScienceCategorySurgery-
dc.subject.keywordPlusBODY-MASS INDEX-
dc.subject.keywordPlusNASOPHARYNGEAL CARCINOMA-
dc.subject.keywordPlusPREDICTING MORTALITY-
dc.subject.keywordPlusSURVIVAL-
dc.subject.keywordPlusFAT-
dc.subject.keywordPlusRADIOTHERAPY-
dc.subject.keywordPlusMETAANALYSIS-
dc.subject.keywordPlusASSOCIATION-
dc.subject.keywordPlusDISEASE-
dc.subject.keywordPlusOBESITY-
dc.subject.keywordAuthoradipose tissue-
dc.subject.keywordAuthorfluorodeoxyglucose F18-
dc.subject.keywordAuthorhead and neck cancer-
dc.subject.keywordAuthorpositron emission tomography-
dc.subject.keywordAuthorprognosis-
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Radiology > 1. Journal Articles
College of Medicine > Department of Otorhinolaryngology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Park, JAE HONG photo

Park, JAE HONG
College of Medicine (Department of Otorhinolaryngology)
Read more

Altmetrics

Total Views & Downloads

BROWSE