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The Effects of Hypoglycemic Agents on Non-alcoholic Fatty Liver Disease: Focused on Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon Like Peptide -1 Receptor Agonistsopen access
- Authors
- Jung, Chan-Hee; Mok, Ji-Oh
- Issue Date
- Mar-2019
- Publisher
- 대한비만학회
- Keywords
- Sodium-glucose cotransporter 2 inhibitor; Glucagon-like peptide-1 receptor agonist; Non-alcoholic fatty liver disease; Type 2 diabetes mellitus
- Citation
- Journal of Obesity & Metabolic Syndrome, v.28, no.1, pp 18 - 29
- Pages
- 12
- Journal Title
- Journal of Obesity & Metabolic Syndrome
- Volume
- 28
- Number
- 1
- Start Page
- 18
- End Page
- 29
- ISSN
- 2508-6235
2508-7576
- Abstract
- The only known, effective intervention for non-alcoholic fatty liver disease (NAFLD) is weight loss, and there is no approved pharmacotherapy. Recently, new hypoglycemic agents, such as sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1RAs), and their effects on NAFLD have received substantial interest. Herein, we review the currently available human studies regarding the effects of SGLT2 inhibitors and GLP-1RAs on NAFLD/non-alcoholic steatohepatitis in patients with type 2 diabetes mellitus, and we describe the possible mechanisms explaining the positive effects of these agents on NAFLD).
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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Related Researcher
- Mok, Ji Oh
- College of Medicine (Department of Internal Medicine)