Clinical Characteristics of Oral Allergy Syndrome in Children with Atopic Dermatitis and Birch Sensitization: a Single Center Study
DC Field | Value | Language |
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dc.contributor.author | Kim, Kang-in | - |
dc.contributor.author | Lee, Bomi | - |
dc.contributor.author | Min, Taek Ki | - |
dc.contributor.author | Lee, Jeongho | - |
dc.contributor.author | Pyun, Bok Yang | - |
dc.contributor.author | Jeon, You Hoon | - |
dc.date.accessioned | 2021-08-11T10:23:54Z | - |
dc.date.available | 2021-08-11T10:23:54Z | - |
dc.date.issued | 2019-01-14 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/4788 | - |
dc.description.abstract | Background: Oral allergy syndrome (OAS) is an immunoglobulin E (IgE)-mediated hypersensitivity that occurs frequently in older children with pollen sensitization. This study focused on the clinical characteristics of OAS in children with atopic dermatitis (AD) and birch sensitization. Method: s: A total of 186 patients aged 2-18 years with AD and birch sensitization were enrolled in this study between January 2016 and March 2017. Their levels of serum total IgE and birch- and ragweed-specific IgE (sIgE) were measured using ImmunoCAP (Thermo Fisher Scientific, Uppsala, Sweden). Information regarding causative foods and symptoms were obtained via interviews. The patients were divided into 3 groups according to their ages group 1, 2-6 years; group 2, 7-12 years; and group 3, 13-18 years). Results: Eighty-one of the 186 (43.5%) children with AD who were sensitized to birch pollen were diagnosed as having OAS. The prevalence of OAS in group 1 (the children who had AD and birch sensitization aged 2-6 years) was 36.6%. A greater predominance of men was noted in the non-OAS group (77.1%) compared to the OAS group (60.5%). Apples were the most common causative food in group 2 and 3 while kiwis were the most common cause of OAS in group 1. There was a statistically significant correlation between birch-sIgE levels and the prevalence of OAS (P= 0.000). The cut-offvalue was 6.77 kU(A)/L with 55.6% sensitivity and 79.0% specificity (area tinder the curve 0.653). Conclusion: In our study, the prevalence of OAS in children with All and birch sensitization was 43.5%. Even in the preschool age group, the prevalence of OAS was considerable. Patients with high levels of birch-sIgE were more likely to have OAS. Clinicians should therefore be vigilant about OAS in patients with a high degree of sensitization to birch pollen and even young children if they have birch sensitization. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한의학회 | - |
dc.title | Clinical Characteristics of Oral Allergy Syndrome in Children with Atopic Dermatitis and Birch Sensitization: a Single Center Study | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3346/jkms.2019.34.e11 | - |
dc.identifier.scopusid | 2-s2.0-85059908877 | - |
dc.identifier.wosid | 000455718600004 | - |
dc.identifier.bibliographicCitation | Journal of Korean Medical Science, v.34, no.2 | - |
dc.citation.title | Journal of Korean Medical Science | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002432647 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | FOOD ALLERGY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | SYNDROME OAS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | IGE | - |
dc.subject.keywordPlus | HYPERSENSITIVITY | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordAuthor | Oral Allergy Syndrome | - |
dc.subject.keywordAuthor | Children | - |
dc.subject.keywordAuthor | Atopic Dermatitis | - |
dc.subject.keywordAuthor | Birch | - |
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