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Radiomics in Oncological PET/CT: Clinical Applications

Authors
Lee, Jeong WonLee, Sang Mi
Issue Date
Jun-2018
Publisher
대한핵의학회
Keywords
Positron emission tomography; Neoplasm; Radiomics; Heterogeneity; Image analysis
Citation
Nuclear Medicine and Molecular Imaging, v.52, no.3, pp 170 - 189
Pages
20
Journal Title
Nuclear Medicine and Molecular Imaging
Volume
52
Number
3
Start Page
170
End Page
189
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/5948
DOI
10.1007/s13139-017-0500-y
ISSN
1869-3474
1869-3482
Abstract
F-18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is widely used for staging, evaluating treatment response, and predicting prognosis in malignant diseases. FDG uptake and volumetric PET parameters such as metabolic tumor volume have been used and are still used as conventional PET parameters to assess biological characteristics of tumors. However, in recent years, additional features derived from PET images by computational processing have been found to reflect intratumoral heterogeneity, which is related to biological tumor features, and to provide additional predictive and prognostic information, which leads to the concept of radiomics. In this review, we focus on recent clinical studies of malignant diseases that investigated intratumoral heterogeneity on PET/CT, and we discuss its clinical role in various cancers.
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