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Psychiatric symptoms delay the diagnosis of anti-LGI1 encephalitis
- Authors
- Jang, Yoonhyuk; Lee, Soon-Tae; Lim, Jung-Ah; Kim, Tae-Joon; Jun, Jin-Sun; Moon, Jangsup; Sunwoo, Jun-Sang; Jung, Keun-Hwa; Park, Kyung-Il; Jung, Ki-Young; Kim, Manho; Lee, Sang Kun; Chu, Kon
- Issue Date
- 15-Apr-2018
- Publisher
- Elsevier BV
- Keywords
- Psychiatric symptom; Senile depression; Dementia; Epilepsy-related psychosis; Prognostic factor; Anti-LGI1 encephalitis
- Citation
- Journal of Neuroimmunology, v.317, pp 8 - 14
- Pages
- 7
- Journal Title
- Journal of Neuroimmunology
- Volume
- 317
- Start Page
- 8
- End Page
- 14
- ISSN
- 0165-5728
1872-8421
- Abstract
- The aim of this study was to analyze the detailed characteristics of the psychiatric symptoms in patients with anti-LGI1 encephalitis. Of 16 patients, ten showed psychiatric symptoms as the initial manifestations. All 10 patients experienced mood-related symptoms. The time to immune therapy was longer in those with initial psychiatric symptoms compared to those without them. Initial manifestation of psychiatric symptoms in patients with anti-LGI1 encephalitis may be a poor prognostic factor, at least in the short term, in that it misleads both the patients and the clinicians to neglect the typically accompanied symptoms of the disease such as faciobrachial dystonic seizure, delaying the timing of immune therapy.
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Collections - College of Medicine > Department of Neurology > 1. Journal Articles
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