급성 저주파 감각신경성 난청에서 스테로이드 용량에 따른 단기적 치료 효과 비교

Abstract

Background and Objectives Acute low-tone sensorineural hearing loss refers to a condi-tion wherein thresholds increase only at low frequencies in pure-tone audiometry. Systemic steroid treatment is commonly used for acute low-tone sensorineural hearing loss without ver-tigo, but there has been no established treatment in most clinical researches. The purpose of this study is to compare and analyze the short-term effects of high- and half-dose oral steroid therapy on patients suffering from acute low-tone sensorineural hearing loss without vertigo. Subjects and Method Forty-six patients diagnosed with acute low-tone sensorineural hear-ing loss were divided into two groups and treated with high-dose (24 patients) and half-dose (22 patients) steroids, respectively. A retrospective analysis was conducted on their medical records. Results There were no significant differences between the two groups in any of the follow-ing: age, sex ratio, duration of symptoms before treatment, pure-tone hearing thresholds, low frequency hearing thresholds and speech intelligibility. However, both groups showed signifi-cant differences in hearing thresholds before and after treatment. In addition, no significant difference was noted in the recovery and recurrence rate between the two groups.Conclusion According to the results of this study, there is no difference in treatment effect between the high- and half-dose groups. Therefore, half-dose steroids may be used as a treat-ment option for acute low tone sensorineural hearing loss.