마이코플라즈마 감염과 동반된 급성 출혈성 뇌척수염A Case of Acute Hemorrhagic Encephalomyelitis associated with Mycoplasma Pneumoniae Infection
- Other Titles
- A Case of Acute Hemorrhagic Encephalomyelitis associated with Mycoplasma Pneumoniae Infection
- Authors
- 최윤하; 이정호; 서은숙
- Issue Date
- 2018
- Publisher
- 대한소아신경학회
- Keywords
- Acute hemorrhagic encephalomyelitis (AHEM); Mycoplasma pneumoniae
- Citation
- 대한소아신경학회지, v.26, no.1, pp.70 - 73
- Journal Title
- 대한소아신경학회지
- Volume
- 26
- Number
- 1
- Start Page
- 70
- End Page
- 73
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6754
- DOI
- 10.26815/jkcns.2018.26.1.70
- ISSN
- 1226-6884
- Abstract
- Acute hemorrhagic encephalomyelitis (AHEM) is a severe form of encephalitis characterized by fulminant clinical course and presence of hemorrhagic necrosis of the white matter. Mycoplasma pneumoniae (M. pneumoniae) have severe central nervous syndrome complication with encephalitis as that most common pediatric manifestations, but have been extremely rare report with AHME. A 10-year-old boy was referred to emergency room because of drowsy mental status, weakness of left side extremities and truncal ataxia. His deep tendon reflexes were hyperactive, neck stiffness sign and Babinski sign were both positive. Motor power were decreased on the both left upper and lower extremities. The sequences of T2-weighted and gradient recalled echo (GRE) showed hyper-intense lesions on multifocal white natter areas with hemorrhagic signal. Cerebrospinal fluid (CSF) analysis showed the pleocytosis with neutrophil dominant. The results of deoxyribonucleic acid (DNA) test and culture of M. pneumoniae were reported negative in CSF, but immunoglobulin M (IgM) was positive in blood. He received intravenous high dose corticosteroid and macrolide. After discharge, his neurologic function gradually returned to normal including sitting and standing without support. We reported the previously healthy boy with M. pneumonia related AHEM. The early diagnosis with brain MRI and the aggressive immunosuppressive treatment may be beneficial for recovery.
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Collections - College of Medicine > Department of Pediatrics > 1. Journal Articles
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