Detailed Information

Cited 0 time in webofscience Cited 33 time in scopus
Metadata Downloads

Impact of Mild Cognitive Impairment on Mortality and Cause of Death in the Elderly

Authors
Bin Bae, JongHan, Ji WonKwak, Kyung PhilKim, Bong JoKim, Shin GyeomKim, Jeong LanKim, Tae HuiRyu, Seung-HoMoon, Seok WooPark, Joon HyukYoun, Jong ChulLee, Dong YoungLee, Dong WooLee, Seok BumLee, Jung JaeJhoo, Jin HyeongKim, Ki Woong
Issue Date
2018
Publisher
IOS Press
Keywords
Cause of death; cognitive dysfunction; death; epidemiology; neurocognitive disorders; mortality
Citation
Journal of Alzheimer's Disease, v.64, no.2, pp 607 - 616
Pages
10
Journal Title
Journal of Alzheimer's Disease
Volume
64
Number
2
Start Page
607
End Page
616
URI
https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/6826
DOI
10.3233/JAD-171182
ISSN
1387-2877
1875-8908
Abstract
Background: Mild cognitive impairment (MCI) is a cognitive state that lies on the continuum between normal aging and dementia, and the prevalence of MCI is higher than dementia. However, the risk for mortality of people with MCI has been far less studied than that of people with dementia, and the population attributable risk percent (PAR%) of death attributable to MCI has not been estimated yet. Objective: To investigate the impact of MCI on mortality and the cause of death in the elderly, and to estimate the PAR% of deaths attributable to MCI. Methods: Data came from 7,315 elderly subjects aged >= 60 years without dementia from two cohort studies with diagnostic assessments of MCI at baseline. Deaths among participants were confirmed through the nationwide mortality database of Statistics Korea. Results: MCI increased the risk of mortality in a multivariate Cox proportional model adjusting for age, sex, education, smoking, alcohol drinking, chronic illness, depression, vascular components, and cohort (hazard ratio = 1.59, 95% confidence interval 1.30, 1.94). PAR% of death attributable to MCI was 10.7% for age 65- 74 years, 16.0% for age 75-84 years, and 24.2% for age >= 85 years. In the elderly with MCI, mortality risks from cerebrovascular disease, respiratory disease, and external causes were higher than in the cognitively normal elderly. Conclusions: Our results suggest that the mortality risk of MCI in Asian countries may be comparable to that in Western countries, and MCI can contribute to the death of the elderly as much as dementia.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Psychiatry > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Shin Gyeom photo

Kim, Shin Gyeom
College of Medicine (Department of Psychiatry)
Read more

Altmetrics

Total Views & Downloads

BROWSE