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Capsule, septum, and T2 hyperintense foci for differentiation between large hepatocellular carcinoma (>= 5 cm) and intrahepatic cholangiocarcinoma on gadoxetic acid MRI

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dc.contributor.authorHwang, Jiyoung-
dc.contributor.authorKim, Young Kon-
dc.contributor.authorMin, Ji Hye-
dc.contributor.authorChoi, Seo-Youn-
dc.contributor.authorJeong, Woo Kyung-
dc.contributor.authorHong, Seong Sook-
dc.contributor.authorKim, Hyun-joo-
dc.contributor.authorAhn, Soohyun-
dc.contributor.authorAhn, Hyeon Seon-
dc.date.accessioned2021-08-11T14:24:02Z-
dc.date.available2021-08-11T14:24:02Z-
dc.date.issued2017-11-
dc.identifier.issn0938-7994-
dc.identifier.issn1432-1084-
dc.identifier.urihttps://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7090-
dc.description.abstractObjective To determine the added value of capsule, septum, and T2 hyperintense foci for differentiating large hepatocellular carcinoma (HCC; >= 5 cm) from intrahepatic cholangiocarcinoma (ICC) using gadoxetic acid MRI. Methods The study included 116 patients (94 men, 22 women; mean age, 56.8 years) with surgically confirmed HCCs (n = 87, 5.0-18.0 cm) or ICCs (n = 29, 5.0-14.0 cm) who underwent gadoxetic acid MRI. Three observers independently reviewed MRIs in two sessions, examining enhancement patterns only and then adding capsule, septum, and T2 hyperintense foci. Reviewers used a five-point scale to score accuracy, sensitivity, and specificity. Results A significant increase was observed in accuracy when ancillary features (96.1-98.3%) were added compared to enhancement pattern only (83.6-88.4%; p ae<currency> 0.02). Sensitivity was significantly increased with combined reading (97.1-98.3%) compared to enhancement features only (81.6-88.5%; p ae<currency> 0.006) for two observers, with no difference in specificity (84.5-89.7% vs. 86.2-98.3%; p > 0.05). We found substantial to excellent interobserver agreement for ancillary features (0.598-0.976). Conclusion Adding capsule, septum, and T2 hyperintense foci to enhancement patterns for gadoxetic acid MRI increased diagnostic performance for characterizing large HCC by differentiating it from ICC.-
dc.format.extent10-
dc.language영어-
dc.language.isoENG-
dc.publisherSpringer Verlag-
dc.titleCapsule, septum, and T2 hyperintense foci for differentiation between large hepatocellular carcinoma (>= 5 cm) and intrahepatic cholangiocarcinoma on gadoxetic acid MRI-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1007/s00330-017-4846-4-
dc.identifier.scopusid2-s2.0-85019206066-
dc.identifier.wosid000412820500016-
dc.identifier.bibliographicCitationEuropean Radiology, v.27, no.11, pp 4581 - 4590-
dc.citation.titleEuropean Radiology-
dc.citation.volume27-
dc.citation.number11-
dc.citation.startPage4581-
dc.citation.endPage4590-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaRadiology, Nuclear Medicine & Medical Imaging-
dc.relation.journalWebOfScienceCategoryRadiology, Nuclear Medicine & Medical Imaging-
dc.subject.keywordPlusENHANCED MRI-
dc.subject.keywordPlusFORMING CHOLANGIOCARCINOMA-
dc.subject.keywordPlusHISTOPATHOLOGIC FINDINGS-
dc.subject.keywordPlusCLINICAL-SIGNIFICANCE-
dc.subject.keywordPlusCOMPUTED-TOMOGRAPHY-
dc.subject.keywordPlusHEPATOBILIARY PHASE-
dc.subject.keywordPlusCIRRHOTIC LIVER-
dc.subject.keywordPlusDIAGNOSIS-
dc.subject.keywordPlusMASS-
dc.subject.keywordPlusCONTRAST-
dc.subject.keywordAuthorGadoxetic acid-
dc.subject.keywordAuthorMRI-
dc.subject.keywordAuthorHepatocellular carcinoma-
dc.subject.keywordAuthorCholangiocarcinoma-
dc.subject.keywordAuthorAncillary feature-
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