Characteristics of early repolarization parameters and prognostic implications in the general ambulatory Korean population
- Authors
- Cho, Min Soo; Kwon, Chang Hee; Nam, Gi-Byoung; Lee, Woo Seok; Hwang, Ki Won; Kim, Yong Giun; Choi, Hyung Oh; Kim, Sung-Hwan; Kim, Jeongsoon; Nam, Hyo-Jung; Min, Sun-Yang; Kim, Minsu; Lee, Ji Hyun; Hwang, You Mi; Jo, Uk; Kim, Jun; Choi, Kee-Joon; Kim, You-Ho
- Issue Date
- 15-Jan-2017
- Publisher
- Elsevier BV
- Keywords
- Early repolarization; J wave; Electrocardiography; Mortality; Outcome; Age distribution
- Citation
- International Journal of Cardiology, v.227, pp 571 - 576
- Pages
- 6
- Journal Title
- International Journal of Cardiology
- Volume
- 227
- Start Page
- 571
- End Page
- 576
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/7839
- DOI
- 10.1016/j.ijcard.2016.10.099
- ISSN
- 0167-5273
1874-1754
- Abstract
- Background: We tested a hypothesis that the 2 fundamental components of early repolarization (ER), J wave and ST elevation (STE) might have different prevalence and prognostic implications. Methods: The study population comprised 26,345 general ambulatory Korean subjects (mean 48.0 +/- 10.2 years old, 53.2% male) who underwent medical checkups from January 2002 to December 2002. ER was found in 2950 subjects (11.2%), who were divided into 3 groups (J [J wave only, n = 1874, 7.1%], JST [both J wave and STE, n = 489, 1.8%], and ST [STE only, n = 587, 2.3%]). Results: The prevalence of STE decreased with age, whereas]) waves remained al a constant level in all age groups. The most common pattern of ER was the J pattern, with a horizontal/descending ST segment in the inferior leads; in lateral precordial leads, ST or JST patterns with ascending ST segments were more common. During the mean follow-up of 126.0 +/- 11.1 months, a fatal of 710 subjects died (2.7%). Subjects in the J group were at higher risk (Hazard ratio 1.60, 95% confidence interval 127-2.01, p < 0.001), while those in the JST and ST groups showed similar survival outcomes compared to controls without J waves or STE. Conclusions: J waves and STE showed different age and lead distributions and prognostic implications. The presence of the J wave itself was associated with a higher relative risk of mortality. However, due to the low event rate, its clinical significance appears to be limited. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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