Rejuvenation Using Platelet-rich Plasma and Lipofilling for Vaginal Atrophy and Lichen Sclerosus

Abstract

Vaginal atrophy is a common condition among peri- and post-menopausal women. Symptoms of vaginal dryness, pruritus,irritation, loss of subcutaneous fat, sparse pubic hair and dyspareunia occur due to decreased estrogen level. Estrogen-basedtreatments are effective. But many patients are reluctant to be treated due to health concerns. As alternatives, we exploredthe efficacy of platelet-rich plasma (PRP) and lipofilling. A 67-year-old female patient with vaginal atrophy was referred to ourdepartment. Treatment using estrogen cream had failed to improve patient’s symptoms. Diminished volume and aged look ofgenitalia were also major concerns. We treated her using lipofilling mixed with PRP. A total of 40 cc of autologous fat mixed withPRP was transferred to labia majora. Lipofilling with PRP relieved the clinical symptoms. Missing fullness and tone was correctedand the augmented volume was well maintained. White patchy lesions of lichen sclerosus on labia minora also improved. Lipofilling with PRP relieved symptoms, restored contour of the labia majora and achieved remission of lichen sclerosus on labiaminora. As vulvar lesions were repaired and the aged appearance of genitalia was rejuvenated, both functional and cosmeticoutcomes were satisfactory. Lipofilling with PRP can be effective for vaginal atrophy and lichen sclerosus. (J Menopausal Med2017;23:63-68)