Use of a Comprehensive Geriatric Assessment to Predict Short-Term Postoperative Outcome in Elderly Patients With Colorectal Cancer
- Authors
- Lee, Yoon Hyun; Oh, Heung-Kwon; Kim, Duck-Woo; Ihn, Myong Hoon; Kim, Jee Hyun; Son, Il Tae; Kang, Sung Il; Kim, Gwang Il; Ahn, Soyeon; Kang, Sung-Bum
- Issue Date
- Oct-2016
- Publisher
- 대한대장항문학회
- Keywords
- Colorectal neoplasms; Comprehensive geriatric assessment; Complication
- Citation
- Annals of Coloproctology, v.32, no.5, pp 161 - 169
- Pages
- 9
- Journal Title
- Annals of Coloproctology
- Volume
- 32
- Number
- 5
- Start Page
- 161
- End Page
- 169
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/8746
- DOI
- 10.3393/ac.2016.32.5.161
- ISSN
- 2287-9714
2287-9722
- Abstract
- Purpose: This study was conducted to identify the effectiveness of a preoperative comprehensive geriatric assessment (CGA) for predicting postoperative morbidity in elderly patients who underwent surgery for colorectal cancer. Methods: Elderly patients (>= 70 years old) who underwent surgery for colorectal cancer at a tertiary hospital in Korea were identified, and their cases were analyzed using data from a prospectively collected database to establish an association between major postsurgical complications and 'high-risk' patient as defined by the CGA. Results: A total of 240 patients, with a mean age of 76.7 +/- 5.2 years, were enrolled. Ninety-five patients (39.6%) were classified as "high-risk" and 99 patients (41.3%) as having postoperative complications. The univariate analysis indicated that risk factors for postoperative complications were age, American Society of Anesthesiologists physical status classification, serum hemoglobin, carcinoembryonic antigen, cancer stage, and "high-risk" status. The multivariable analyses indicated that "high-risk" status (odds ratio, 2.107; 95% confidence interval, 1.168-3.804; P = 0.013) and elevated preoperative carcinoembryonic antigen (odds ratio, 2.561; 95% confidence interval, 1.346-4.871, P = 0.004) were independently associated with postoperative complications. A multivariable analysis of the individual CGA domains indicated that high comorbidities and low activities of daily living were significantly related with postoperative complications. Conclusion: A preoperative CGA indicating "high-risk" was associated with major postoperative complications in elderly patients who underwent surgery for colorectal cancer. Thus, using the CGA to identify elderly colorectal-cancer patients who should be given more care during postoperative management may be clinically beneficial.
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Collections - College of Medicine > Department of General Surgery > 1. Journal Articles
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