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Frequent rhabdomyolysis in anti-NMDA receptor encephalitis
- Authors
- Lim, Jung-Ah; Lee, Soon-Tae; Kim, Tae-Joon; Moon, Jangsup; Sunwoo, Jun-Sang; Byun, Jung-Ick; Jung, Keun-Hwa; Jung, Ki-Young; Chu, Kon; Lee, Sang Kun
- Issue Date
- 15-Sep-2016
- Publisher
- Elsevier BV
- Keywords
- Encephalitis; NMDA; Autoimmune encephalitis; Rhabdomyolysis
- Citation
- Journal of Neuroimmunology, v.298, pp 178 - 180
- Pages
- 3
- Journal Title
- Journal of Neuroimmunology
- Volume
- 298
- Start Page
- 178
- End Page
- 180
- ISSN
- 0165-5728
1872-8421
- Abstract
- The aim of this study was to analyze the clinical presentation and provocation factors of rhabdomyolysis in anti-NMDAR encephalitis. Among the 16 patients with anti-NMDAR encephalitis in our institutional cohort, nine patients had elevated CK enzyme levels and clinical evidence of rhabdomyolysis. Rhabdomyolysis was more frequent after immunotherapy. The use of dopamine receptor blocker (DRB) increased the risk of rhabdomyolysis. None of the patients without rhabdomyolysis received DRBs. Rhabdomyolysis is a frequent complication in anti-NMDAR encephalitis and more common after immunotherapy and the use of DRBs increases the risk. Therefore, DRBs should be administered carefully in patients with anti-NMDAR encephalitis. (C) 2016 Elsevier B.V. All rights reserved.
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Collections - College of Medicine > Department of Neurology > 1. Journal Articles
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