Efficacy and Safety of Therapeutic Endoscopic Retrograde Cholangiopancreatography in the Elderly Over 80 Years
- Authors
- Han, Su Jung; Lee, Tae Hoon; Kang, Byong Il; Choi, Hyun Jong; Lee, Yun Nah; Cha, Sang-Woo; Moon, Jong Ho; Cho, Young Deok; Park, Sang Hum; Kim, Sun-Joo
- Issue Date
- Jul-2016
- Publisher
- Kluwer Academic/Plenum Publishers
- Keywords
- Endoscopic retrograde cholangiopancreatography; Elderly; Efficacy; Safety; Complications
- Citation
- Digestive Diseases and Sciences, v.61, no.7, pp 2094 - 2101
- Pages
- 8
- Journal Title
- Digestive Diseases and Sciences
- Volume
- 61
- Number
- 7
- Start Page
- 2094
- End Page
- 2101
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/8983
- DOI
- 10.1007/s10620-016-4064-y
- ISSN
- 0163-2116
1573-2568
- Abstract
- Concern regarding the safety and efficacy of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) in elderly patients is increasing as a result of the aging society. However, there are limited data, especially in the super-aged elderly. This study aimed to evaluate the efficacy and safety of therapeutic ERCP in patients a parts per thousand yen80 years of age. Patients 80 years of age or older (n = 312) and younger than 65 years (n = 312) who underwent therapeutic ERCP from June 2006 to April 2014 were randomly selected and analyzed retrospectively. The main outcome measurements were therapeutic ERCP-related complications and clinical outcomes in the two groups. Choledocholithiasis combined with gallbladder stone was the most common indication for ERCP in both groups. Comorbid diseases (70.5 and 29.8 %, p < 0.001) and the use of anti-thrombotic drugs (18.6 and 1.6 %, p < 0.001) were more frequent in the super-aged group. The mean procedure time was longer, and the frequency of second ERCP was more common in the super-aged group. However, the technical success rate (94.9 and 97.4 %, p = 0.096) and the procedure-related complication rate (4.8 and 5.8 %, p = 0.592) were not different between the two groups. Post-ERCP pancreatitis occurred in 1.3 % of the super-aged group and in 2.9 % of the control group (p = 0.262). Cardiopulmonary complications occurred in 1.9 % of patients in each group (p = 1.0). Therapeutic ERCP is comparable in terms of efficacy and safety between patients a parts per thousand yen80 years and those < 65 years of age, although the elderly group had a higher rate of comorbid diseases and used anti-thrombotic drugs more frequently.
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Collections - College of Medicine > Department of Internal Medicine > 1. Journal Articles
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