Determination of human serum albumin using a single-walled carbon nanotube-FET modified with bromocresol green
DC Field | Value | Language |
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dc.contributor.author | Kim, Bongsu | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.date.accessioned | 2021-08-11T17:45:25Z | - |
dc.date.available | 2021-08-11T17:45:25Z | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0026-3672 | - |
dc.identifier.issn | 1436-5073 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9236 | - |
dc.description.abstract | We developed a nanoscale-based assay for the detection of human serum albumin (HSA) by placing the HSA indicator probe, bromocresol green (BCG) on the single-walled carbon nanotubes on a field effect transistor (swCNT-FET) via simple coating. Bovine serum albumin (BSA) was used as a blocking agent to reduce non-specific binding. The selective binding of HSA onto BCG alters the charge of the dye and the surface, and this causes a change in the conductance of the swCNT-FET. The assay is highly sensitive and selective for HSA, with an 18.6 nga <...mL(-1) detection limit. The high sensitivity and selectivity of the assay is ascribed to appropriate BSA blocking and the instantaneous response of sensitive swCNT-FET to rapid BCG-HSA binding, which minimizes non-specific binding and overcomes the time-sensitivity of BCG-HSA binding, respectively. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Determination of human serum albumin using a single-walled carbon nanotube-FET modified with bromocresol green | - |
dc.type | Article | - |
dc.publisher.location | 오스트리아 | - |
dc.identifier.doi | 10.1007/s00604-016-1815-6 | - |
dc.identifier.scopusid | 2-s2.0-84961188017 | - |
dc.identifier.wosid | 000373146100029 | - |
dc.identifier.bibliographicCitation | Microchimica Acta, v.183, no.4, pp 1513 - 1518 | - |
dc.citation.title | Microchimica Acta | - |
dc.citation.volume | 183 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1513 | - |
dc.citation.endPage | 1518 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | 580 FLUORESCENCE ASSAY | - |
dc.subject.keywordPlus | DIABETES-MELLITUS | - |
dc.subject.keywordPlus | URINARY ALBUMIN | - |
dc.subject.keywordPlus | BLOOD-SERUM | - |
dc.subject.keywordPlus | MICROALBUMINURIA | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | BLUE | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | QUANTIFICATION | - |
dc.subject.keywordAuthor | Nanosensor | - |
dc.subject.keywordAuthor | Field effect transistor | - |
dc.subject.keywordAuthor | Self-assembled monolayer | - |
dc.subject.keywordAuthor | Photolithography | - |
dc.subject.keywordAuthor | Conductivity sensor | - |
dc.subject.keywordAuthor | Amperometry | - |
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