Relationship Between Serum Vitamin D Levels and Symptoms of Depression in Stroke Patients
- Authors
- Kim, Sang-Hyun; Seok, Hyun; Kim, Dong Suk
- Issue Date
- Feb-2016
- Publisher
- 대한재활의학회
- Keywords
- 25-hydroxyvitamin D (25-OHD); Stroke; Depression
- Citation
- Annals of Rehabilitation Medicine, v.40, no.1, pp 120 - 125
- Pages
- 6
- Journal Title
- Annals of Rehabilitation Medicine
- Volume
- 40
- Number
- 1
- Start Page
- 120
- End Page
- 125
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9407
- DOI
- 10.5535/arm.2016.40.1.120
- ISSN
- 2234-0645
2234-0653
- Abstract
- Objective To investigate the correlation between depressive symptoms and serum vitamin D levels in stroke patients. Methods In total, 126 stroke patients were analyzed. The 25-hydroxyvitamin D (25-OHD) concentration of each patient was used to determine their vitamin D status. Depressive symptoms were assessed using the Beck Depression Inventory II (BDI-II) and the Patient Health Questionnaire 9 (PHQ-9). Functional status was evaluated with the Korean version of the Modified Barthel Index (K-MBI). We compared the clinical questionnaires of a vitamin D-deficient group and a normal group, and evaluated the correlations between BDI-II, PHQ-9, K-MBI, and serum 25-OHD levels. Results In the vitamin D-deficient group, BDI-II (16.0 +/- 12.1) and PHQ-9 (7.4 +/- 4.2) scores were significantly higher than those of the normal group (BDI-II, 9.1 +/- 7.2; PHQ-9, 4.2 +/- 2.9; p<0.01). In a Spearman correlation analysis, a significant negative correlation was found between serum 25-OHD levels and BDI-II (Spearman r=0.177, p=0.048), but there were no significant correlations between serum 25-OHD levels and PHQ-9 or K-MBI. Conclusion Vitamin D deficiency was correlated with the symptoms of depression in stroke patients.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Physical Medicine and Rehabilitation > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.