Glufosinate 중독 환자의 신경학적 예후 인자로서 APACHE II Score의 유용성Utility of the APACHE II Score as a Neurologic Prognostic Factor for Glufosinate Intoxicated Patients
- Other Titles
- Utility of the APACHE II Score as a Neurologic Prognostic Factor for Glufosinate Intoxicated Patients
- Authors
- 유대한; 이정원; 최재형; 정동길; 이동욱; 이영주; 조영신; 박준범; 정혜진; 문형준
- Issue Date
- 2016
- Publisher
- 대한임상독성학회
- Keywords
- Phosphinothricin; Herbicides; APACHE; Prognosis
- Citation
- 대한임상독성학회지, v.14, no.2, pp 107 - 114
- Pages
- 8
- Journal Title
- 대한임상독성학회지
- Volume
- 14
- Number
- 2
- Start Page
- 107
- End Page
- 114
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9569
- DOI
- 10.22537/jksct.2016.14.2.107
- ISSN
- 1738-1320
2508-6332
- Abstract
- Purpose: The incidence of glufosinate poisoning is gradually increasing, and it can be fatal if severe poisoning occurs. However, factors useful for predicting the post-discharge neurological prognosis of patients who have ingested glufosinate have yet to be identified. Our objective was to evaluate the utility of the acute physiology and chronic health evaluation (APACHE) II score measured in the emergency department for predicting the neurological prognosis.
Methods: From April 2012 to August 2014, we conducted a retrospective study of patients who had ingested glufosinate. The outcome of the patients at discharge was defined by the Cerebral Performance Category Score (CPC). The patients were divided into a good prognosis group (CPC 1, 2) and a poor prognosis group (CPC 3, 4, 5), after which the APACHE II scores were compared. The Hosmer-Lemeshow test and the area under the receiver operating characteristic (ROC) curve from patients determined calibration and discrimination.
Results: A total of 76 patients were enrolled (good prognosis group: 67 vs poor prognosis group: 9). The cut-off value for the APACHE II score was 12 and the area under the curve value was 0.891. The Hosmer and Lemeshow C statistic χ2 was 7.414 (p=0.387), indicating good calibration for APACHE II.
Conclusion: The APACHE II score is useful at predicting the neurological prognosis of patients who have ingested glufosinate.
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Collections - College of Medicine > Department of Emergency Medicine > 1. Journal Articles
- College of Medicine > Department of Emergency Medicine > 1. Journal Articles
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