Cognition and Visit-to-Visit Variability of Blood Pressure and Heart Rate in De Novo Patients with Parkinson’s DiseaseCognition and Visit-to-Visit Variability of Blood Pressure and Heart Rate in De Novo Patients with Parkinson’s Disease
- Other Titles
- Cognition and Visit-to-Visit Variability of Blood Pressure and Heart Rate in De Novo Patients with Parkinson’s Disease
- Authors
- 권겸일; 표선종; 이혜미; 서우근; 고성범
- Issue Date
- 2016
- Publisher
- 대한파킨슨병및이상운동질환학회
- Keywords
- Parkinson’s disease; blood pressure; heart rate; variability; cognition
- Citation
- Journal Of Movement Disorders, v.9, no.3, pp 166 - 170
- Pages
- 5
- Journal Title
- Journal Of Movement Disorders
- Volume
- 9
- Number
- 3
- Start Page
- 166
- End Page
- 170
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9680
- ISSN
- 2005-940X
2093-4939
- Abstract
- Objective We sought to identify whether the characteristics of long-term visit-to-visit blood pressure (BP) and heart rate (HR) are related to baseline cognitive profiles in, Parkinson’s disease (PD).
Methods We selected drug-naïve PD patients who visited our hospital at least 10 times with a baseline assessment of the Seoul neuropsychological battery. BP and HR were measured at each visit, and the variability of the systolic BP/diastolic BP (DBP) and HR was derived from the parameters of serial 10 office visits. Mild cognitive impairment (MCI) in PD patients was determined according to the proposed criteria with a cut-off value of z-score ≤ -2.
Results Forty-seven patients with PD (mean follow-up duration = 22.3 months) were enrolled in the study. Compared with non-MCI PD patients, MCI PD patients revealed a significant increase in HR and/or variability in DBP.
Conclusion This exploratory study showed that baseline cognition in drug-naïve PD patients might be related to the visit-to-visit variability of DBP and/or HR.
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Collections - College of Medicine > Department of Neurology > 1. Journal Articles
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