The performance of tele-cervicography for detection of preinvasive and invasive disease of the uterine cervix as an adjunctive test to Pap smears
- Authors
- Nam, Kyehyun; Kim, Soo-Nyung; Sim, Seung-hyuk; Han, Seijun
- Issue Date
- 2016
- Publisher
- Termedia
- Keywords
- cervicography; cervical cancer; cervical neoplasia; screening.
- Citation
- Wspolczesna Onkologia, v.20, no.5, pp 402 - 406
- Pages
- 5
- Journal Title
- Wspolczesna Onkologia
- Volume
- 20
- Number
- 5
- Start Page
- 402
- End Page
- 406
- URI
- https://scholarworks.bwise.kr/sch/handle/2021.sw.sch/9910
- DOI
- 10.5114/wo.2016.64604
- ISSN
- 1428-2526
1897-4309
- Abstract
- Aim of the study: To evaluate the diagnostic capacity of tele-cervicography for the detection of cervical neoplasia as an adjunctive test with Papanicolaou (Pap) smears. Material and methods: Pap smear and tele-cervicography were performed on each subject. Histologic results were obtained for all patients. Results: Of the 863 females who had a tele-cervigram, 252 (29.2%) had a positive result. Of the 60 histologically confirmed cases of high-grade squamous intraepithelial lesions (HSILs), 56 (93.3%) were detected by tele-cervicography, including 16 (26.7%) with a positive grade of 1 and 40 (66.7%) with a positive grade of 2. With the positive threshold of tele-cervicography set as any positive grade (P0 to P3), the overall sensitivity was 94.0% (95% CI: 88.0-97.3%), the specificity was 80.9% (95% CI: 80.0-81.5%), and the positive likelihood ratio was 4.94 (95% CI: 4.23-5.77) for the detection of HSILs or cancer. The combination of tele-cervicography with Pap smear testing for the detection of HSILs or cancer resulted in an increase in sensitivity from 84.6% (Pap only: cutoff = atypical squamous cells of undetermined significance or more severe) to 98.3% (Pap plus tele-cervicography: cutoff = P0 or more severe). Conclusions: The sensitivity of tele-cervicography was higher than that of cytology for the detection of cervical neoplasia, and combining the two tests increased the sensitivity. Tele-cervicography can be considered a useful complementary tool to cytology.
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Collections - College of Medicine > Department of Obstetrics and Gynecology > 1. Journal Articles
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