Incremental Detection Rate of Dysplasia and Sessile Serrated Polyps/Adenomas Using Narrow-Band Imaging and Dye Spray Chromoendoscopy in Addition to High-Definition Endoscopy in Patients with Long-Standing Extensive Ulcerative Colitis: Segmental Tandem Endoscopic Studyopen access
- Authors
- Kim, J.E.[Kim, J.E.]; Choi, C.W.[Choi, C.W.]; Hong, S.N.[Hong, S.N.]; Song, J.H.[Song, J.H.]; Kim, E.R.[Kim, E.R.]; Chang, D.K.[Chang, D.K.]; Kim, Y.-H.[Kim, Y.-H.]
- Issue Date
- Feb-2023
- Publisher
- MDPI
- Keywords
- chromoendoscopy; high-definition endoscopy; narrow band imaging; sessile serrated lesion; ulcerative colitis
- Citation
- Diagnostics, v.13, no.3
- Indexed
- SCIE
SCOPUS
- Journal Title
- Diagnostics
- Volume
- 13
- Number
- 3
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/103339
- DOI
- 10.3390/diagnostics13030516
- ISSN
- 2075-4418
- Abstract
- High-definition (HD) endoscopy is recommended in surveillance colonoscopy for detecting dysplasia in patients with ulcerative colitis (UC). Dye-spray chromoendoscopy (DCE) and narrow-band imaging (NBI) are often used as adjunctive techniques of white-light endoscopy (WLE) in real-world practice. However, the incremental detection ability of DCE and NBI added to HD-WLE for dysplasia and serrated lesions has not yet been evaluated using tandem endoscopy in patients with long-standing extensive UC. We enrolled patients with extensive UC for >8 years who were in clinical remission (partial Mayo score < 2) at the Samsung Medical Center in Seoul, Republic of Korea. HD-WLE was performed first. Subsequently, HD-NBI and HD-DCE with indigo carmine were performed using the segmental tandem colonoscopy technique. A total of 40 patients were eligible, and data obtained from 33 patients were analyzed. The incremental detection rates (IDRs) for dysplasia and serrated lesions were calculated. HD-WLE detected three dysplasia and five sessile serrated adenomas/polyps (SSAs/Ps). HD-NBI and HD-DCE did not detect additional dysplasia (IDR = 0%; 95% confidence interval (CI): 0–56.2%). HD-NBI identified one missed SSA/P (IDR = 7.7%; 95% CI: 1.4–33.3%), and HD-DCE detected seven missed SSAs/Ps (IDR = 53.9%; 95% CI: 29.1–76.8%). Logistic regression found that HD-DCE increased the detection of SSAs/Ps compared to HD-WLE and/or HD-NBI (odds ratio (OR) = 3.16, 95% CI: 0.83–11.92, p = 0.08). DCE in addition to HD-WLE improved the detection of SSAs/Ps, but not dysplasia, in patients with long-standing extensive UC. © 2023 by the authors.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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