Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantationopen access
- Authors
- Lee, N.[Lee, Nuri]; Cha, S.[Cha, Sora]; Kim, J.[Kim, Jongman]; Lee, Y.[Lee, Yunmi]; Kang, E.[Kang, Enjin]; Kim, H.J.[Kim, Hyun Jung]; Hong, S.H.[Hong, Seung Hui]; Rhu, J.[Rhu, Jinsoo]; Choi, G.-S.[Choi, Gyu-Seong]; Joh, J.-W.[Joh, Jae-Won]
- Issue Date
- Sep-2023
- Publisher
- Korean Surgical Society
- Keywords
- Brain death donor; Delayed graft function; Liver regeneration; Mechanical ventilator; Primary graft dysfunction
- Citation
- Annals of Surgical Treatment and Research, v.105, no.3, pp.141 - 147
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Annals of Surgical Treatment and Research
- Volume
- 105
- Number
- 3
- Start Page
- 141
- End Page
- 147
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/108923
- DOI
- 10.4174/astr.2023.105.3.141
- ISSN
- 2288-6575
- Abstract
- Purpose: Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified. Methods: From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared. Results: Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT. Conclusion: Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support. Copyright © 2023, the Korean Surgical Society.
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