Molecular and cellular organization of odorant binding protein genes in Drosophilaopen access
- Authors
- Park, Keehyun; Choi, Hyungjun; Han, I Joon; Asefa, Wayessa Rahel; Jeong, Chaiyoung; Yu, Seungyun; Jeong, Hanhee; Choi, Minkook; Yoon, Sung-Eun; Kim, Young-Joon; Choi, Min Sung; Kwon, Jae Young
- Issue Date
- 15-May-2024
- Publisher
- Elsevier Ltd
- Keywords
- Bitter sensing; Drosophila melanogaster; GAL4-Driven expression; Odorant binding proteins
- Citation
- Heliyon, v.10, no.9
- Indexed
- SCIE
SCOPUS
- Journal Title
- Heliyon
- Volume
- 10
- Number
- 9
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/110687
- DOI
- 10.1016/j.heliyon.2024.e29358
- ISSN
- 2405-8440
2405-8440
- Abstract
- Chemosensation is important for the survival and reproduction of animals. The odorant binding proteins (OBPs) are thought to be involved in chemosensation together with chemosensory receptors. While OBPs were initially considered to deliver hydrophobic odorants to olfactory receptors in the aqueous lymph solution, recent studies suggest more complex roles in various organs. Here, we use GAL4 transgenes to systematically analyze the expression patterns of all 52 members of the Obp gene family and 3 related chemosensory protein genes in adult Drosophila, focusing on chemosensory organs such as the antenna, maxillary palp, pharynx, and labellum, and other organs such as the brain, ventral nerve cord, leg, wing, and intestine. The OBPs were observed to express in diverse organs and in multiple cell types, suggesting that these proteins can indeed carry out diverse functional roles. Also, we constructed 10 labellar-expressing Obp mutants, and obtained behavioral evidence that these OBPs may be involved in bitter sensing. The resources we constructed should be useful for future Drosophila OBP gene family research. © 2024 The Authors
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