Safety and Efficacy of Biodegradable Polymer-biolimus-eluting Stents (BP-BES) Compared with Durable Polymer-everolimus-eluting Stents (DP-EES) in Patients Undergoing Complex Percutaneous Coronary Interventionopen accessSafety and efficacy of biodegradable polymer-biolimus-eluting stents (BP-BES) compared with durable polymer-everolimus-eluting stents (DP-EES) in patients undergoing complex percutaneous coronary intervention
- Other Titles
- Safety and efficacy of biodegradable polymer-biolimus-eluting stents (BP-BES) compared with durable polymer-everolimus-eluting stents (DP-EES) in patients undergoing complex percutaneous coronary intervention
- Authors
- Song, PS[Song, Pil Sang]; Park, KT[Park, Kyu Tae]; Kim, MJ[Kim, Min Jeong]; Jeon, KH[Jeon, Ki-Hyun]; Park, JS[Park, Jin-Sik]; Choi, RK[Choi, Rak Kyeong]; Song, YB[Song, Young Bin]; Choi, SH[Choi, Seung-Hyuk]; Choi, JH[Choi, Jin-Ho]; Lee, SH[Lee, Sang Hoon]; Gwon, HC[Gwon, Hyeon-Cheol]; Jeong, JO[Jeong, Jin-Ok]; Im, ES[Im, Eul Soon]; Kim, SW[Kim, Sang Wook]; Chun, WJ[Chun, Woo Jung]; Oh, JH[Oh, Ju Hyeon]; Hahn, JY[Hahn, Joo-Yong]
- Issue Date
- Jan-2019
- Publisher
- KOREAN SOC CARDIOLOGY
- Keywords
- Coronary artery disease; Percutaneous coronary intervention; Drug-eluting stents
- Citation
- KOREAN CIRCULATION JOURNAL, v.49, no.1, pp.69 - 80
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- KOREAN CIRCULATION JOURNAL
- Volume
- 49
- Number
- 1
- Start Page
- 69
- End Page
- 80
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/11528
- DOI
- 10.4070/kcj.2018.0097
- ISSN
- 1738-5520
- Abstract
- Background and Objectives: There are no data comparing clinical outcomes of complex percutaneous coronary intervention (PCI) between biodegradable polymer-biolimus-eluting stents (BP-BES) and durable polymer-everolimus-eluting stents (DP-EES). We sought to evaluate the safety and efficacy of BP-BES compared with DP-EES in patients undergoing complex PCI. Methods: Patients enrolled in the SMART-DESK registry were stratified into 2 categories based on the complexity of PCI. Complex PCI was defined as having at least one of the following features: unprotected left main lesion, >= 2 lesions treated, total stent length >40 mm, minimal stent diameter <= 2.5 mm, or bifurcation as target lesion. The primary outcome was target lesion failure (TLF), defined as a composite of cardiac death, target vessel-related myocardial infarction (TV-MI), or target lesion revascularization (TLR) at 2 years of follow-up. Results: Of1,999 patients, 1,145 (57.3%) underwent complex PCI: 521 patients were treated with BP-BES and 624 with DP-EES. In propensity-score matching analysis (481 pairs), the risks of TLF (3.8% vs. 5.2%, adjusted hazard ratio [HR], 0.578; 95% confidence interval [CI], 0.246-1.359; p=0.209), cardiac death (2.5% vs. 2.5%, adjusted HR, 0.787; 95% CI, 0.244-2.539; p=0.689), TV-MI (0.5% vs. 0.4%, adjusted HR, 1.128; 95% CI, 0.157-8.093; p=0.905), and TLR (1.1% vs. 2.9%, adjusted HR, 0.390; 95% CI, 0.139-1.095; p=0.074) did not differ between 2 stent groups after complex PCI. Conclusions: Clinical outcomes of BP-BES were comparable to those of DP-EES at 2 years after complex PCI. Our data suggest that use of BP-BES is acceptable, even for complex PCI.
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