Characteristics and clinical outcomes of critically ill cancer patients admitted to Korean intensive care unitsopen access
- Authors
- Na, S.J.[Na, S.J.]; Ha, T.S.[Ha, T.S.]; Koh, Y.[Koh, Y.]; Suh, G.Y.[Suh, G.Y.]; Koh, S.O.[Koh, S.O.]; Lim, C.-M.[Lim, C.-M.]; Choi, W.-I.[Choi, W.-I.]; Lee, Y.-J.[Lee, Y.-J.]; Kim, S.C.[Kim, S.C.]; Chon, G.R.[Chon, G.R.]; Kim, J.H.[Kim, J.H.]; Kim, J.Y.[Kim, J.Y.]; Lim, J.[Lim, J.]; Park, S.[Park, S.]; Kim, H.C.[Kim, H.C.]; Lee, J.H.[Lee, J.H.]; Lee, J.H.[Lee, J.H.]; Park, J.[Park, J.]; Cho, J.[Cho, J.]; Jeon, K.[Jeon, K.]; Validation of Simplified Acute Physiology Score 3 in Korean Intensive care unit (VSKI) study group[Validation of Simplified Acute Physiology Score 3 in Korean Intensive care unit (VSKI) study group]; and the Korean Study Group On Respiratory Failure (KOSREF)[and the Korean Study Group On Respiratory Failure (KOSREF)]
- Issue Date
- Aug-2018
- Publisher
- Korean Society of Critical Care Medicine
- Keywords
- Cancer; Critical care; Epidemiology; Hematologic neoplasm; Mortality
- Citation
- Acute and Critical Care, v.33, no.3, pp.121 - 129
- Indexed
- SCOPUS
KCI
- Journal Title
- Acute and Critical Care
- Volume
- 33
- Number
- 3
- Start Page
- 121
- End Page
- 129
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/21629
- DOI
- 10.4266/acc.2018.00143
- ISSN
- 2586-6052
- Abstract
- Background: The objective of this study was to investigate the characteristics and clinical outcomes of critically ill cancer patients admitted to intensive care units (ICUs) in Korea. Methods: This was a retrospective cohort study that analyzed prospective collected data from the Validation of Simplified Acute Physiology Score 3 (SAPS3) in Korean ICU (VSKI) study, which is a nationwide, multicenter, and prospective study that considered 5,063 patients from 22 ICUs in Korea over a period of 7 months. Among them, patients older than 18 years of age who were diagnosed with solid or hematologic malignancies prior to admission to the ICU were included in the present study. Results: During the study period, a total of 1,762 cancer patients were admitted to the ICUs and 833 of them were deemed eligible for analysis. Six hundred fifty-eight (79%) had solid tumors and 175 (21%) had hematologic malignancies, respectively. Respiratory problems (30.1%) was the most common reason leading to ICU admission. Patients with hematologic malignancies had higher Sequential Organ Failure Assessment (12 vs. 8, P < 0.001) and SAPS3 (71 vs. 69, P < 0.001) values and were more likely to be associated with chemotherapy, steroid therapy, and immunocompromised status versus patients with solid tumors. The use of inotropes/vasopressors, mechanical ventilation, and/or continuous renal replacement therapy was more frequently required in hematologic malignancy patients. Mortality rates in the ICU (41.7% vs. 24.6%, P < 0.001) and hospital (53.1% vs. 38.6%, P = 0.002) were higher in hematologic malignancy patients than in solid tumor patients. Conclusions: Cancer patients accounted for one-third of all patients admitted to the studied ICUs in Korea. Clinical characteristics were different according to the type of malignancy. Patients with hematologic malignancies had a worse prognosis than did patients with solid tumor. Copyright © 2018 The Korean Society of Critical Care Medicine
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