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카바페넴 내성 그람음성균 감염의 항생제 치료Antimicrobial Therapy for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria

Other Titles
Antimicrobial Therapy for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria
Authors
위유미[위유미]강철인[강철인]
Issue Date
2018
Publisher
대한내과학회
Keywords
Gram-negative bacteria; Carbapenem; Drug resistance; Treatment outcome; 그람음성균; 카바페넴; 약제내성; 치료 효과
Citation
대한내과학회지, v.93, no.5, pp.439 - 446
Indexed
KCI
OTHER
Journal Title
대한내과학회지
Volume
93
Number
5
Start Page
439
End Page
446
URI
https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/21825
ISSN
1738-9364
Abstract
Carbapenem-resistance emerging in Gram-negative pathogens, such as Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii, has become a major human health problem globally. The therapeutic options available for carbapenem- resistant pathogens are very limited. Antibiotics such as colistin, tigecycline, fosfomycin, and aminoglycosides are often the only ones that can be used to treat carbapenem-resistant pathogens. Carbapenem may still be an option in certain circumstances. The administration of combination therapy for carbapenem-resistant pathogens is controversial. This review presents the current knowledge of available antimicrobial therapeutic options for infections due to carbapenem-resistant pathogens in Korea.
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