노인성 우울증 환자와 정상 노인에서 인지기능의 비교 및 우울증 증상 변화와의 관련성 평가Comparisons of Neurocognitive Functions in Patients with Late-Life Depression versus Normal Elderly, and Association with Changes of Depressive Symptoms in a 3-Month Follow-Up
- Other Titles
- Comparisons of Neurocognitive Functions in Patients with Late-Life Depression versus Normal Elderly, and Association with Changes of Depressive Symptoms in a 3-Month Follow-Up
- Authors
- 김혜원[김혜원]; 최관우[최관우]; 나은진[나은진]; 이한경[이한경]; 전홍진[전홍진]
- Issue Date
- 2018
- Publisher
- 대한노인정신의학회
- Keywords
- Late-life depression; Neuropsychological assessment; Cognition.
- Citation
- 노인정신의학, v.22, no.2, pp.76 - 83
- Indexed
- KCI
- Journal Title
- 노인정신의학
- Volume
- 22
- Number
- 2
- Start Page
- 76
- End Page
- 83
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/22625
- ISSN
- 1226-6329
- Abstract
- Objective:This study aimed to investigate the neurocognitive functions of patients with late-life depression compared to healthy controls and their association with improvement of depressive symptoms. Methods:We compared the results of neurocognitive tests between 41 patients with late-life depression and 20 healthy controls at baseline and 3 months later prospectively. And then we investigated the association of change of cognitive function and improvement of depressive symptoms in patients with late-life depression. Results:Patients with late-life depression showed significantly impaired results in neurocognitive tests especially in domains of language, memory and frontal executive function compared to healthy control. However, after 3 months of treatment of depression, there was no association between the change of results of neurocognitive tests and the changes of scores of Hamilton Depression Rating Scale (HAM-D). Conclusion:Impairment of cognitive functions in late-life depression includes the domains of language, memory and executive function and after 3 months of treatment of depression, there was no association of improvement of depressive symptom and cognitive change in patients with late-life depression.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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