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A New ent-kaurane Diterpene Glycoside from Seeds of Pharbitis nil
- Authors
- Woo, KW[Woo, Kyeong Wan]; Park, KJ[Park, Kyoung Jin]; Choi, SZ[Choi, Sang Zin]; Son, MW[Son, Mi Won]; Kim, KH[Kim, Ki Hyun]; Lee, KR[Lee, Kang Ro]
- Issue Date
- May-2017
- Publisher
- SPRINGER
- Keywords
- Pharbitis nil; Convolvulaceae; ent-kaurane type diterpene; pharboside H
- Citation
- CHEMISTRY OF NATURAL COMPOUNDS, v.53, no.3, pp.468 - 471
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY OF NATURAL COMPOUNDS
- Volume
- 53
- Number
- 3
- Start Page
- 468
- End Page
- 471
- ISSN
- 0009-3130
- Abstract
- A new ent-kaurane diterpene glycoside, pharboside H (1), and three known compounds, benzyl beta-D-glucopyranoside (2), 1-(4'-O-glucopyranosyl-4'-hydroxy-3',5'-dimethoxyphenyl)-2{2'',6''-dimethoxy-4''-[1-(E) propen-3-ol]-phenoxy}-propane-l,3-diol (3), and butyl caffeate (4), were isolated from the seeds of Pharbitis nil. The structure of the new compound 1 was elucidated by 1D and 2D data analysis and enzyme hydrolysis. All the isolated compounds 1-4 were reported from this source for the first time. Compounds 1-4 were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.
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