Emergence of community-genotype methicillin- resistant Staphylococcus aureus in Korean hospitals: Clinical characteristics of nosocomial infections by community-genotype strainopen access
- Authors
- Joo, E.-J.[Joo, E.-J.]; Chung, D.R.[Chung, D.R.]; Kim, S.H.[ Kim, S.H.]; Baek, J.Y.[ Baek, J.Y.]; Lee, N.Y.[Lee, N.Y.]; Cho, S.Y.[ Cho, S.Y.]; Ha, Y.E.[ Ha, Y.E.]; Kang, C.-I.[Kang, C.-I.]; Peck, K.R.[Peck, K.R.]; Song, J.-H.[Song, J.-H.]
- Issue Date
- 2017
- Publisher
- Korean Society for Chemotherapy
- Citation
- Infection and Chemotherapy, v.49, no.2, pp.109 - 116
- Indexed
- SCOPUS
KCI
- Journal Title
- Infection and Chemotherapy
- Volume
- 49
- Number
- 2
- Start Page
- 109
- End Page
- 116
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/33432
- DOI
- 10.3947/ic.2017.49.2.109
- ISSN
- 2093-2340
- Abstract
- Background: As community-genotype methicillin-resistant Staphylococcus aureus (MRSA) strains spread into hospitals, the genotypes of the MRSA strains causing hospital-acquired (HA) infections have become more diverse. We describe clinical characteristics of nosocomial MRSA infections by a community-genotype of sequence type (ST) 72. Materials and Methods: A case-control study was designed among patients with HA-MRSA infections. Forty patients with infections caused by ST72-MRSA SCCmec type IV were selected as cases. Cases were matched to the controls with 106 patients infected with ST5/ST239 MRSA, which are representative hospital genotypes in Korea. Results: Patients infected with ST72 isolates were younger than those with ST5/ST239 isolates. Female gender predominated among ST72 MRSA group compared to ST5/ST239 MRSA group. Solid tumor was a more frequent underlying disease in MRSA infections by ST72 isolates, whereas underlying renal, lung, heart, and neurologic diseases were more frequently found in those by ST5/ST239 isolates. The most common type of infection was pneumonia in both ST72 and ST5/ST239 groups (45.0% vs. 51.9%), followed by skin and soft tissue infection (SSTI). Female gender and underlying solid tumor were identified to be independent predictors for MRSA infections by ST72 isolates. All-cause mortality rates (20.0% vs. 30.2%) were not different between the groups. Conclusion: A community-genotype MRSA, ST72 isolate has emerged as a nosocomial pathogen presenting as hospital-acquired pneumonia and SSTI. Although differences in underlying disorders were found, the distribution of infection type and mortality rate did not differ between the groups. © 2017 by The Korean Society of Infectious Diseases.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Medicine > Department of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/33432)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.