Modified Core Biopsy Technique to Increase Diagnostic Yields for Well-Circumscribed Indeterminate Thyroid Nodules: A Retrospective Analysisopen access
- Authors
- Han S.[Han S.]; Shin J.H.[Shin J.H.]; Hahn S.Y.[Hahn S.Y.]; Oh Y.L.[Oh Y.L.]
- Issue Date
- Jun-2016
- Publisher
- AMER SOC NEURORADIOLOGY
- Citation
- AMERICAN JOURNAL OF NEURORADIOLOGY, v.37, no.6, pp.1155 - 1159
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN JOURNAL OF NEURORADIOLOGY
- Volume
- 37
- Number
- 6
- Start Page
- 1155
- End Page
- 1159
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/36407
- DOI
- 10.3174/ajnr.A4650
- ISSN
- 0195-6108
- Abstract
- BACKGROUND AND PURPOSE: The results of conventional core biopsy for some thyroid nodules with indeterminate cytology have still remained indeterminate. The aim of this study was to evaluate whether the ultrasonography-guided core needle biopsy technique containing the nodule, capsular portion, and surrounding parenchyma was more effective than a conventional method in enhancing diagnostic yield for circumscribed solid thyroid nodules without malignant sonographic features. MATERIALS AND METHODS: This retrospective comparative study evaluated 26 thyroid nodules in 26 consecutive patients between 2006 and 2010. They were biopsied by using a conventional method, and 61 nodules from 60 patients were biopsied by using a modified ultrasonography-guided core needle biopsy technique in 2013. The patients enrolled in this study presented with circumscribed solid thyroid nodules without malignant sonographic features, classified as nondiagnostic or atypia/follicular lesions of undetermined significance at previous cytology. The ultrasonography-guided core needle biopsy results of the 2 groups were compared. RESULTS: The rate of inconclusive ultrasonography-guided core needle biopsy results was 34.6% (9/26) in the conventional group and 11.4% (7/61) in the modified technique group (P =.018). There was no significant difference in the mean size of the nodules between the 2 groups (P = .134). The malignancy rate was 33% (3/9) for the conventional group and 52% (27/52) for the modified technique group (P =.473). The most common malignant pathology was a follicular variant of papillary thyroid carcinoma and follicular adenoma was the most common benign lesion. CONCLUSIONS: For circumscribed solid nodules without malignant sonographic features with indeterminate cytology, the ultrasonography-guided core needle biopsy technique containing the nodule, capsular portion, and surrounding parenchyma is more effective in diagnostic yield compared with a conventional method that biopsies the intranodular portion.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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