Clinical Implications of Early Exercise Treadmill Testing after Percutaneous Coronary Intervention in the Drug-eluting Stent EraClinical Implications of Early Exercise Treadmill Testing after Percutaneous Coronary Intervention in the Drug-eluting Stent Era
- Other Titles
- Clinical Implications of Early Exercise Treadmill Testing after Percutaneous Coronary Intervention in the Drug-eluting Stent Era
- Authors
- Cho, SW[Cho, Sung Woo]; Yang, JH[Yang, Jeong Hoon]; Park, TK[Park, Taek Kyu]; Lee, JM[Lee, Joo Myung]; Song, YB[Song, Young Bin]; Hahn, JY[Hahn, Joo Yong]; Choi, JH[Choi, Jin Ho]; Gwon, HC[Gwon, Hyeon Cheol]; Lee, SH[Lee, Sang Hoon]; Choi, SH[Choi, Seung Hyuk]
- Issue Date
- 13-Jul-2020
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Exercise Treadmill Testing; Percutaneous Coronary Intervention
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.35, no.27, pp.1 - 11
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 35
- Number
- 27
- Start Page
- 1
- End Page
- 11
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/3867
- DOI
- 10.3346/jkms.2020.35.e229
- ISSN
- 1011-8934
- Abstract
- Background: Limited data are available on the clinical meaning of early routine exercise treadmill testing (ETT) after percutaneous coronary intervention (PCI) in the drug-eluting stent era. We aimed to determine the clinical utility and implications of early routine ETT after PCI. Methods: This was a single-center, prospective cohort study. A total of 776 patients underwent ETT within 3 months after index PCI were analyzed. We classified patients into ETT positive (+) and negative (-) groups and compared major adverse cardiac events (MACE) including all-cause death, myocardial infarction, and coronary revascularization. Results: The median follow-up duration was 19.6 months (interquartile range, 15.4 to 33.5 months). ETT was positive for 63 patients (17.1%) with single-vessel disease (VD) and 150 patients (36.9%) with multi-VD. Previous PCI, absence of thrombotic lesion, multi-VD, and residual Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) score > 8 were independent predictors of ETT (+). Compared with the ETT (-) group, the ETT (+) group was associated with increased risk of MACE for patients with single-VD (18.1% vs. 52.3%; adjusted hazard ratio [HR], 2.67; 95% confidence interval [Cl], 1.10-6.49; P= 0.03) and residual SYNTAX score <= 8 (26.5% vs. 42.1%; adjusted HR, 1.90; 95% CI, 1.09-3.30; P= 0.02), but not for patients with multi-VD and residual SYNTAX score > 8. Conclusion: Early routine ETT after PCI might be helpful for predicting clinical outcomes in patients with single-VD and residual SYNTAX score <= 8 but not multi-VD and residual SYNTAX score > 8.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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