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Backbone NMR Assignments of an Uncharacterized Protein, SF1002 from Shigella flexneri 5a M90TBackbone NMR Assignments of an Uncharacterized Protein, SF1002 from Shigella flexneri 5a M90T

Other Titles
Backbone NMR Assignments of an Uncharacterized Protein, SF1002 from Shigella flexneri 5a M90T
Authors
이유섭[이유섭]윤원수[윤원수]정일[정일]정가영[정가영]원형식[원형식]서민덕[서민덕]
Issue Date
2015
Publisher
한국자기공명학회
Keywords
Shigella flexneri; backbone NMR assignments; structural genomics
Citation
Journal of the Korean Magnetic Resonance Society, v.19, no.1, pp.36 - 41
Indexed
KCI
Journal Title
Journal of the Korean Magnetic Resonance Society
Volume
19
Number
1
Start Page
36
End Page
41
URI
https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/45358
DOI
10.6564/JKMRS.2014.19.1.036
ISSN
1226-6531
Abstract
The causative agent of shigellosis, Shigella flexneri, is a Gram-negative anaerobic bacterial pathogen that causes one of the most infectious bacterial dysenteries in humans. It originates infection by invading cells of the colonic epithelium using a type III secretion system. Despite S. flexneri is closely linked with the human disease, structural study is very deficient. Here, we have initiated NMR study of SF1002 which is the uncharacterized protein from S. flexneri strain 5a M90T. Based on a series of triple resonance spectra, sequence-specific assignments of the backbone amide resonances of SF1002 could be completed. This NMR study would contribute to the structural genomics of S.flexneri.
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