Differences in early speech patterns between Parkinson variant of multiple system atrophy and Parkinson's disease
- Authors
- Huh Y.E.[Huh Y.E.]; Park J.[Park J.]; Suh M.K.[Suh M.K.]; Lee S.E.[Lee S.E.]; Kim J.[Kim J.]; Jeong Y.[Jeong Y.]; Kim H.-T.[Kim H.-T.]; Cho J.W.[Cho J.W.]
- Issue Date
- 2015
- Keywords
- Multiple system atrophy; Parkinson' s disease; Speech; Acoustic analysis; Perceptual analysis
- Citation
- Brain and Language, v.147, pp.14 - 20
- Journal Title
- Brain and Language
- Volume
- 147
- Start Page
- 14
- End Page
- 20
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/48974
- DOI
- 10.1016/j.bandl.2015.04.007
- Abstract
- In Parkinson variant of multiple system atrophy (MSA-P), patterns of early speech impairment and their distinguishing features from Parkinson's disease (PD) require further exploration. Here, we compared speech data among patients with early-stage MSA-P, PD, and healthy subjects using quantitative acoustic and perceptual analyses. Variables were analyzed for men and women in view of gender-specific features of speech. Acoustic analysis revealed that male patients with MSA-P exhibited more profound speech abnormalities than those with PD, regarding increased voice pitch, prolonged pause time, and reduced speech rate. This might be due to widespread pathology of MSA-P in nigrostriatal or extra-striatal structures related to speech production. Although several perceptual measures were mildly impaired in MSA-P and PD patients, none of these parameters showed a significant difference between patient groups. Detailed speech analysis using acoustic measures may help distinguish between MSA-P and PD early in the disease process. © 2015 Elsevier Inc.
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- Appears in
Collections - Medicine > Department of Medicine > 1. Journal Articles
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