Gadoxetic acid-enhanced MRI for T-staging of gallbladder carcinoma: emphasis on liver invasion
- Authors
- Hwang, J[Hwang, J.]; Kim, YK[Kim, Y. K.]; Choi, D[Choi, D.]; Rhim, H[Rhim, H.]; Lee, WJ[Lee, W. J.]; Hong, SS[Hong, S. S.]; Kim, HJ[Kim, H-J]; Chang, YW[Chang, Y-W]
- Issue Date
- Jan-2014
- Publisher
- BRITISH INST RADIOLOGY
- Citation
- BRITISH JOURNAL OF RADIOLOGY, v.87, no.1033
- Indexed
- SCIE
SCOPUS
- Journal Title
- BRITISH JOURNAL OF RADIOLOGY
- Volume
- 87
- Number
- 1033
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/54437
- DOI
- 10.1259/bjr.20130608
- ISSN
- 0007-1285
- Abstract
- Objective: To evaluate the diagnostic performance of gadoxetic acid-enhanced MRI with an emphasis on the usefulness of the hepatobiliary phase (HBP) in T-staging of gallbladder carcinoma. Methods: 66 patients with surgically confirmed gallbladder carcinoma underwent MRI. Two radiologists independently reviewed two sets of gadoxetic acid-enhanced MRI without and with the HBP. Local tumour spread was evaluated according to T-staging, and the results were compared with pathological findings. The diagnostic performance of two image sets to differentiate each T-stage was compared. Results: The sensitivities of MRI with the HBP to differentiate T1 vs >= T2 lesions, <= T2 vs >= T3 lesions and <= T3 vs T4 lesions were 96.3%, 85.7% and 100% for Observer 1 and 92.6%, 95.2% and 100% for Observer 2, respectively (p < 0.0001). By adding the HBP, the sensitivities to differentiate <= T2 vs >= T3 lesions were increased from 66.7% to 85.7% for Observer 1 and from 81.0% to 95.2% for Observer 2, although there was no significant difference (p > 0.05). The overall accuracies for T-staging were increased from 80.3% to 86.4% for Observer 1, a statistically significant degree (p = 0.046), and from 83.8% to 87.9% for Observer 2 (p > 0.05). The k-value for the two observers indicated excellent agreement. Conclusion: Gadoxetic acid-enhanced MRI provided acceptable diagnostic performance for T-staging of gallbladder carcinoma. Addition of the HBP aids in the detection of liver invasion. Advances in knowledge: In the T-staging of gallbladder carcinoma, gadoxetic acid-enhanced MRI with the HBP may enhance detection of liver invasion.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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