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Phytochemical Constituents of Bletilla striata and Their Cytotoxic ActivityPhytochemical Constituents of Bletilla striata and Their Cytotoxic Activity
- Other Titles
- Phytochemical Constituents of Bletilla striata and Their Cytotoxic Activity
- Issue Date
- 2014
- Publisher
- 한국생약학회
- Keywords
- Bletilla striata; Orchidaceae; Stilbene; Phenanthrene; cytotoxicity
- Citation
- Natural Product Sciences, v.20, no.2, pp.91 - 94
- Indexed
- SCOPUS
KCI
- Journal Title
- Natural Product Sciences
- Volume
- 20
- Number
- 2
- Start Page
- 91
- End Page
- 94
- ISSN
- 1226-3907
- Abstract
- Column chromatographic separation of the MeOH extract from the tubers of Bletilla striata yielded seven phenolic components including four phenanthrenes, 3,7-dihydroxy-2,4-dimethoxyphenanthrene (1), 3,7-dihydroxy-2,4,8-trimethoxyphenanthrene (2), 9,10-dihydro-4,7-dimethoxyphenanthrene-2,8-diol (3), and 9,10-dihydro- 1-(4'-hydroxybenzyl)-4,7-dimethoxyphenanthrene-2,8-diol (4) and three stilbenes, gigantol (5), 3',4''-dihydroxy-5',3'',5''-trimethoxybibenzyl (6), and batatasin III (7). Their structures were determined on the basis of NMR spectroscopic data. Among them, compound 2, 3, and 6 were reported for the first time from this plant. The isolated compounds (1-7) were tested for cytotoxicity against four human tumor cell lines in vitro using a Sulforhodamin B bioassay.
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Collections - Pharmacy > Department of Pharmacy > 1. Journal Articles
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