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The First Korean Case of Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium abscessus Subspecies bolletii in a Patient with Bronchiectasis
- Authors
- 정병호[정병호]; 고원중[고원중]; 김수영[김수영]; 이남용[이남용]; 신성재[신성재]; Jeon, Kyeongman[Jeon, Kyeongman]; 허희재[허희재]; 기창석[기창석]
- Issue Date
- 2014
- Publisher
- 대한결핵및호흡기학회
- Keywords
- Bronchiectasis; Mycobacterium Infections; Nontuberculous; Nontuberculous Mycobacteria; Sequence Analysis; DNA
- Citation
- Tuberculosis and Respiratory Diseases, v.76, no.1, pp.30 - 33
- Indexed
- SCOPUS
KCI
- Journal Title
- Tuberculosis and Respiratory Diseases
- Volume
- 76
- Number
- 1
- Start Page
- 30
- End Page
- 33
- ISSN
- 1738-3536
- Abstract
- We report the first Korean case of lung diseases caused by Mycobacterium abscessus subsp. bolletii in a previously healthy male, except for a previous history of pulmonary tuberculosis and bronchiectasis. All serial isolates are identified as M. abscessus subsp. bolletii by multi-locus sequence analysis based on the hsp65, rpoB, and 16S rRNA fragments. At the genetic level, the isolate has the erm(41) gene with a T28 sequevar, associated with clarithromycin resistance, and no rrl mutation. The isolate is resistant to clarithromycin. Although the symptoms and radiographic findings have improved after combination of antibiotics, the follow-up sputum cultures are persistently positive.
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Related Researcher
- JEON, KYEONG MAN
- Medicine (Medicine)