Increasing recovery of nontuberculous mycobacteria from respiratory specimens over a 10-year period in a tertiary referral hospital in South Koreaopen access
- Authors
- Chang B.[Chang B.]; Jeong B.-H.[Jeong B.-H.]; Kim S.-Y.[Kim S.-Y.]; Kwon O.J.[Kwon O.J.]; Lee N.Y.[Lee N.Y.]; Jeon K.[Jeon K.]; Koh W.-J.[Koh W.-J.]; Ki C.-S.[Ki C.-S.]
- Issue Date
- 2013
- Keywords
- Epidemiology; Korea; Mycobacterium tuberculosis; Nontuberculous mycobacteria
- Citation
- Tuberculosis and Respiratory Diseases, v.75, no.5, pp.199 - 204
- Indexed
- SCOPUS
KCI
- Journal Title
- Tuberculosis and Respiratory Diseases
- Volume
- 75
- Number
- 5
- Start Page
- 199
- End Page
- 204
- URI
- https://scholarworks.bwise.kr/skku/handle/2021.sw.skku/62477
- DOI
- 10.4046/trd.2013.75.5.199
- ISSN
- 1738-3536
- Abstract
- Background: The number of patients with pulmonary disease caused by nontuberculous mycobacteria (NTM) has been increasing worldwide. The aim of this study was to evaluate long-term trends in the NTM recovery rate from respiratory specimens over a 10-year period in a tertiary referral hospital in South Korea. Methods: We retrospectively reviewed the records of mycobacterial cultures of respiratory specimens at Samsung Medical Center from January 2001 to December 2011. Results: During the study period, 32,841 respiratory specimens from 10,563 patients were found to be culture-positive for mycobacteria. These included 12,619 (38%) Mycobacterium tuberculosis and 20,222 (62%) NTM isolates. The proportion of NTM among all positive mycobacterial cultures increased from 43% (548/1,283) in 2001 to 70% (3,341/4,800) in 2011 (p<0.001, test for trend). The recovery rate of NTM isolates from acid-fast bacilli smear-positive specimens increased from 9% (38/417) in 2001 to 64% (1,284/1,997) in 2011 (p<0.001, test for trend). The proportion of positive liquid cultures was higher for NTM than for M. tuberculosis (p<0.001). The most frequently isolated NTM were Mycobacterium avium-intracellulare complex (53%) and Mycobacterium abscessus-massiliense complex (25%). Conclusion: The recovery rate of NTM from respiratory specimens in South Korea has increased steadily. Copyright © 2013 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.
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Collections - Medicine > Department of Medicine > 1. Journal Articles
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