Effects of super-ultramarathon running on cardiac structure and function in middle-aged men

Abstract

BACKGROUND: It remains unclear whether high-intensity exercises result in deformities and reduced function of cardiac muscle. This study hypothesized that participants in a six-day super-ultramarathon (622 km) with sleep deprivation would show serial changes in cardiac structure and function pre-and post-marathon and during the recovery period. METHODS: Cardiac structure and function of middle-aged male volunteers were assessed through echocardiography at pre-and post-marathon, and at 2 recovery periods with a threeday interval. RESULTS: There were no differences in left ventricular end-diastolic and end-systolic dimensions, and end-diastolic volume between pre-and post-marathon. Interventricular septum thickness, left ventricular posterior wall thickness, left ventricular mass, and mass index significantly increased at post-marathon compared to pre-marathon, which decreased during the recovery period. Stroke volume and left ventricular ejection fraction significantly decreased at post-marathon, while both values increased during the recovery period. There were no significant differences in indices for left ventricular relaxation at each assessment period. CONCLUSIONS: An extreme endurance exercise could induce temporary myocardial hypertrophy and contractility reduction. © 2020 Korean Society of Echocardiography.